Effectiveness of amnion allograph injections in patients with degenerative musculoskeletal diseases: a systematic review and meta-analysis.

Objective: Amnion allograft injections have emerged as potential regenerative therapy for degenerative musculoskeletal diseases. In this study, we conducted a systematic review and meta-analysis to evaluate the effectiveness of amnion allograph injections in patients with degenerative musculoskeletal diseases.

Design: A search was conducted across the PubMed, Embase, Cochrane, and Web of Science databases to identify studies reporting on amnion allograft injections in patients with degenerative musculoskeletal diseases.

Construction of MOF-derived Vanadium Nitride Decorated Micro/mesoporous Carbon Nanofibers for Aqueous Zinc-Ion Batteries.

Design and manufacture of cathode materials, with suitable pore structure and high electrical conductivity to matching zinc anode, solving the problem of dissolution and structural degradation of cathode materials for zinc ion batteries (ZIBs), is great significance to the development of ZIBs. Herein, Vanadium Nitride (VN) uniformly decorated N-doped micro/mesoporous carbon nanofibers (VN/N-MCNF) with appropriate porous and reactive sites for Zn2+ is prepared by using V-MOF, as important precursor via electrostatic spinning and pyrolysis technique. As a cathode electrode for ZIBs, the VN/N-MCNF is suitable for diffusion and adsorption of large-sized solvated structured [Zn(H2O)6]2+, for its abundant micro/mesoporous structure and good electrical conductivity.

The complete chloroplast genome of (Bunge) Fisch. & C. A. Mey. 1836 (Asteraceae) and its phylogenetic analysis.

, widely distributed in China, has a 152,467 bp chloroplast genome with a large single-copy (LSC) region of 83,473 bp, a small single-copy (SSC) region of 18,594 bp, a pair of inverted repeat regions (IRs) of 25,194 bp in length. The GC content is 36.46%.

Associations between tooth loss, denture use, and dementia in older Taiwanese adults.

Background: The literature has mainly focused on the association between tooth loss and dementia, and evidence regarding the separate and joint effects of tooth loss and denture use on the risk of dementia is limited. This study investigated the links among tooth loss, denture use, and dementia risk in Taiwanese adults aged 65 years or older.

Methods: This retrospective cohort study utilized data from the 2009 National Health Interview Survey and 2008-2017 National Health Insurance claim records, including the records of 2247 individuals free from dementia treatment in 2008-2009.

In situ structural-functional synchronous dissection of dynamic neuromuscular system via an integrated multimodal wearable patch.

Neuromuscular abnormality is the leading cause of disability in adults. Understanding the complex interplay between muscle structure and function is crucial for effective treatment and rehabilitation. However, the substantial deformation of muscles during movement (up to 40%) poses challenges for accurate assessment.

Eye-Tracking Characteristics: Unveiling Trust Calibration States in Automated Supervisory Control Tasks.

Trust is a crucial human factor in automated supervisory control tasks. To attain appropriate reliance, the operator's trust should be calibrated to reflect the system's capabilities. This study utilized eye-tracking technology to explore novel approaches, given the intrusive, subjective, and sporadic characteristics of existing trust measurement methods.

Identifying cell-type-specific spatially variable genes with ctSVG.

Spatially variable genes (SVGs) reveal the molecular and functional heterogeneity of cells across different spatial regions of a tissue. We found that sample-wide SVGs, identified by previous methods across the whole sample, largely overlap with cell-type marker genes derived from single-cell gene expression, leaving the spatial location information largely underutilized. We developed ctSVG, a computational method specifically tailored for Visium HD spatial transcriptomics at single-cell resolution.

Single-cell transcriptomic analysis of chondrocytes in cartilage and pathogenesis of osteoarthritis.

Chondrocyte is considered the only cell type in cartilage. However, the cell heterogeneity of chondrocytes in human articular cartilage is still not well defined, which hinders our understanding of the pathogenesis of osteoarthritis (OA). Here, we constructed a single-cell transcriptomic atlas of chondrocytes in healthy cartilage and identified nine chondrocyte subsets including homeostatic chondrocytes, proliferate fibrochondrocytes, and hypertrophic chondrocytes (HTC).

Inhibiting autophagy selectively prunes dysfunctional tumor vessels and optimizes the tumor immune microenvironment.

Dysfunctional tumor vasculature, hypoxia, and an immunosuppressive microenvironment are significant barriers to effective cancer therapy. Autophagy, which is critical for maintaining cellular homeostasis and apoptosis resistance, is primarily triggered by hypoxia and nutrient deprivation, conditions prevalent in dysfunctional tumor vessels due to poor circulation. However, the role of autophagy in dysfunctional tumor endothelial cells and its impact on treatment and the tumor microenvironment (TME) remain poorly understood.

Accuracy of interleukin-27 in diagnosing tuberculous pleural effusion: Age should be considered.

Background: Tuberculous pleural effusion (TPE) diagnosis still faces many difficulties and challenges. Some studies have shown that pleural interleukin -27 (IL-27) had a diagnostic potential for TPE. However, their findings are not always consistent.

Are interventional radiology techniques ideal for nonpenetrating splenic injury management: Robust statistical analysis of the Trauma Quality Program database.

Background: Splenic artery embolization (SAE) is increasingly favored for adult blunt splenic injury management. We compared SAE to other splenic injury management strategies using robust statistical techniques.

Materials And Methods: Univariate analyses of demographics and outcomes were performed for four patient groups: observation, SAE, splenic surgery, splenic surgery + SAE in the American College of Surgeons Trauma Quality Program (TQIP) database.

Research on health information avoidance behavior and influencing factors of cancer patients-an empirical analysis based on structural equation modeling.

Objective: To explore the health information avoidance behaviors and influencing factors of cancer patients, and to construct a structural equation model to analyze the mediating roles of self-efficacy and negative emotions in the process of generating health information avoidance behaviors of cancer patients.

Methods: A face-to-face electronic questionnaire was used to collect data. Applying a chi-square test and multivariate logistic regression model to analyze the role of different socio-demographic factors in influencing health information avoidance behavior of cancer patients; applying structural equation modeling to analyze the role mechanism of health information avoidance behavior of cancer patients.

Comparing Large Language Models and Human Programmers for Generating Programming Code.

The performance of seven large language models (LLMs) in generating programming code using various prompt strategies, programming languages, and task difficulties is systematically evaluated. GPT-4 substantially outperforms other LLMs, including Gemini Ultra and Claude 2. The coding performance of GPT-4 varies considerably with different prompt strategies.

New-onset cardiovascular diseases post SARS-CoV-2 infection in an urban population in the Bronx.

This study investigated the incidence of new-onset cardiovascular disorders up to 3.5 years post SARS-CoV-2 infection for 56,400 individuals with COVID-19 and 1,093,904 contemporary controls without COVID-19 in the Montefiore Health System (03/11/2020 to 07/01/2023). Outcomes were new incidence of major adverse cardiovascular event (MACE), arrhythmias, inflammatory heart disease, thrombosis, cerebrovascular disorders, ischemic heart disease and other cardiac disorders between 30 days and (up to) 3.

Correlation analysis of the impact of juvenile on gut microbiota and transcriptome in mice.

Unlabelled: remains a non-negligible global zoonosis, imposing serious socio-economic burdens in endemic regions. The interplay between gut microbiota and the host transcriptome is crucial for maintaining health; however, the impact of juvenile infection on these factors is still poorly understood. This study aimed to investigate their relationship and potential pathogenic mechanisms.

Study on clinical features of early death in older patients with acute promyelocytic leukemia.

This study aimed to analyze the baseline clinical characteristics, as well as the clinical features and risk factors of early death (ED) in older patients with acute promyelocytic leukemia (APL). A retrospective analysis was conducted on 198 consecutive older patients (age ≥ 50 years) with newly diagnosed APL who received arsenic trioxide alone as induction therapy, with 354 younger patients (age < 50 years) as controls. Ten easily obtainable clinical parameters were selected.

Water Microdroplets Promote Spontaneous Oxidation of Amino Acid- and Peptide-related Thiols to Disulfide Bonds.

Disulfide bonds (S-S) play a critical role in modern biochemistry, organic synthesis and prebiotic chemistry. Traditional methods for synthesizing disulfide bonds often rely on oxygen, alkali,  and metal catalysts. Herein, thiol groups involved in amino acids and peptides were spontaneously converted into symmetrical and unsymmetrical disulfide bonds within water microdroplets, without the need for catalysts or oxygen, and under room temperature.

Predicting upper limb motor recovery in subacute stroke patients via fNIRS-measured cerebral functional responses induced by robotic training.

Background: Neural activation induced by upper extremity robot-assisted training (UE-RAT) helps characterize adaptive changes in the brains of poststroke patients, revealing differences in recovery potential among patients. However, it remains unclear whether these task-related neural activities can effectively predict rehabilitation outcomes. In this study, we utilized functional near-infrared spectroscopy (fNIRS) to measure participants' neural activity profiles during resting and UE-RAT tasks and developed models via machine learning to verify whether task-related functional brain responses can predict the recovery of upper limb motor function.

Ion flux regulating with Au-modified separator to realize a homogenize Zn metal deposition.

Aqueous Zn-ion batteries (AZIBs) have attracted widespread attention owing to the feature of low cost, inherent safety and eco-friendliness. However, the poor reversibility of Zn anode severely hinders the practical applicability of AZIBs. Separator modification is an effective way to functionalize the electrode/electrolyte interface and improve the cycling performance.

[Identification and biological characterization of a fungal strain causing root rot of Rehmannia glutinosa].

Root rot is a serious soil-borne disease in the field of Rehmannia glutinosa with continuous cropping obstacle, which se-riously affects the quality and yield of Rehmanniae Radix. In this study, a fungal strain causing root rot of R. glutinosa was isolated from the rhizosphere soil of R.

Enhancing the color and stress tolerance of cherry shrimp (Neocaridina davidi var. red) using astaxanthin and Bidens Pilosa.

This study aimed to evaluate the effects of different concentrations of astaxanthin and Bidens Pilosa compound feed additives on the color and hypoxia tolerance of cherry shrimp (Neocaridina davidi var. red). Color parameters were assessed using CIELAB color space, and differential gene expression related to color and stress was analyzed using reverse transcription quantitative polymerase chain reaction (RT-qPCR) to understand the gene regulatory mechanisms affecting color expression and stability.

Intrinsic Capacity and Life Quality Among Taiwanese Older People: A Cross-Sectional Study.

Intrinsic capacity (IC), an internal composite ability proposed by the World Health Organization, is fundamental to older people's health. The present study examined potential models explaining the association between IC and quality of life (QoL) among older people in Taiwan. Frailty, basic activities of daily living (BADL), and instrumental activities of daily living (IADL) were hypothesized to be mediators in the association between IC and QoL.