The COMT Val158Met polymorphism as an associated risk factor for Parkinson's disease in Asian rather than Caucasian populations.

Background: Catechol-O-methyltransferase (COMT) gene has been reported to be associated with the risk of Parkinson's disease (PD).

Aims: To evaluate the associations of PD risk with COMT polymorphisms.

Materials And Methods: A retrieval of studies that investigated associations between COMT polymorphisms and PD was carried out.