Publications by authors named "Hostert L"

Article Synopsis
  • Surgeons prefer left kidneys for living donor transplants; this study compares outcomes of left versus right kidney donations.
  • Analysis of 7919 nephrectomy and transplantation cases showed right kidney donations had more surgical site infections among donors and poorer immediate outcomes for recipients.
  • Laparoscopic surgery was associated with fewer complications and better long-term graft survival than open surgery, highlighting the importance of surgical technique.
View Article and Find Full Text PDF

Graphene oxide (GO) microfibers with controlled and homogeneous shapes and tunable diameters were fabricated using the 3 dimensional (3D) hydrodynamic focusing concept on a microfluidic device. Thermal and microwave treatments are used to obtain reduced graphene oxide (rGO) microfibers with outstanding electrical properties, thus enabling the development of ionic liquid-gate field-effect transistors (FET) based on graphene derivative microfibers.

View Article and Find Full Text PDF

Escaping the control of natural enemies is thought to heavily influence the establishment success and impact of non-native species. Here, we examined how the profitability of alternative prey in combination with the presence of a competitor and predator aggressive behavior explain individual differences in diet specialization and the consumption of the invasive green porcelain crab by the native mud crab predator Results from bomb calorimetry estimates show that invasive has high caloric value relative to alternative native prey. Laboratory assays indicated that specialization and consumption of invasive was mostly exhibited by large, female , but the presence of a competitor and predator aggressiveness did not influence diet and the consumption of Thus, intrinsic factors (e.

View Article and Find Full Text PDF

A method for quantifying consistent individual differences in schooling behaviour is presented. This method, which utilizes a school of models, improves on previous methods by removing the unwanted variation that is introduced by live stimulus fish while still providing the physiological experience of schooling to the focal fish. Three-spined stickleback Gasterosteus aculeatus observed in the model school assay exhibited consistent individual differences in schooling behaviour.

View Article and Find Full Text PDF
Article Synopsis
  • Transplanting organs from donors with cancer raises important clinical and ethical issues, particularly concerning patient outcomes and informed consent.
  • The study reviewed kidney and liver transplant cases from 2546 procedures between April 2003 and January 2014, focusing on 71 recipients from donors with malignancies.
  • The findings indicated a low risk of cancer transmission, with only two cases of donor-transmitted cancer observed, while recipient survival rates after 1, 3, and 5 years were generally satisfactory for both kidneys and livers, suggesting careful donor selection can lead to successful outcomes.
View Article and Find Full Text PDF

Introduction: A "new" fast track kidney allocation scheme (FTKAS) was implemented in the UK in 2012 for offering of previously declined kidneys. We evaluated the impact of the FTKAS in utilization of declined kidneys and outcome.

Methods: Adult renal transplant centers were surveyed.

View Article and Find Full Text PDF

Renal transplantation is an established method of treating end-stage renal failure. Whilst the majority of procedures follow a standard technique, vascular anomalies may pose intraoperative challenges and, therefore, careful preoperative assessment is warranted. We present a unique, complex case compounded by complete absence of iliac arteries in the left hemipelvis in association with double inferior vena cava in a young recipient.

View Article and Find Full Text PDF

Background: Significant disparity exists in the United Kingdom between the need for organ transplant and supply of deceased donor organs. In the recent years, efforts to increase donation has improved the rate of mainly deceased donors after circulatory death and from older donors. The rate of donation from pediatric population has remained low and those younger than 2 years including neonatal donation has remained largely unexplored.

View Article and Find Full Text PDF

This study was conducted to review the outcomes of patients who had undergone surgical repair of a ureteric stricture following renal transplantation. All patients who developed a ureteric stricture and underwent ureteric reconstruction following renal transplantation, between December 2003 and November 2013, were reviewed. One thousand five hundred and sixty renal transplants were performed during the study period.

View Article and Find Full Text PDF

Behavioral type-environment correlations occur when specific behavioral types of individuals are more common in certain environments. Behavioral type-environment correlations can be generated by several different mechanisms that are probably very common such as niche construction and phenotypic plasticity. Moreover, behavioral type-environment correlations have important ecological and evolutionary implications.

View Article and Find Full Text PDF

Following the influenza A H1N1 (swine flu) pandemic, there remains little evidence informing the safety of transplanting organs from donors suspected or diagnosed with H1N1. Limited guidelines from the major transplant societies leave the use of such organs at the discretion of individual transplant centres, and practice varies considerably both nationally and internationally. We present the largest published series of outcome following transplantation of organs from H1N1 positive donors and demonstrate that these organs can be transplanted safely and with good short-term outcome.

View Article and Find Full Text PDF

The United Kingdom has no national sharing scheme for kidneys received from donation after cardiac death (DCD). Therefore, both kidneys retrieved by a transplant team are implanted at a single unit, often sequentially. This study analyzes the impact of a prolonged cold ischaemia time on the second transplanted kidney and the effects on short-term and long-term outcomes in all our DCD renal implants from 2002 to 2009.

View Article and Find Full Text PDF

The primary purpose of this investigation was to study oxidative demethylation of DNA following ischemia/reperfusion injury (I/RI) that putatively influences posttransplant gene expression in transplanted kidneys. Our hypothesis was that as a result of I/RI, oxidative damage, which is inherent in solid organ transplantation, may lead to aberrant demethylation of cytosine-guanine (CpG) sites within gene promoter regions of DNA. The methylated CpG sites normally contribute to the binding of proteins that render DNA inaccessible to transcription factors.

View Article and Find Full Text PDF

Background: Tissue damage at the time of organ transplantation has a negative impact on the subsequent success of the procedure, both in the immediate and longer term. Hypothermia is the principal element used to prolong organ viability ex vivo, but paradoxically also induces cellular edema through inhibition of energy-dependent adenosine triphosphatases (ATPases). This induces an electrolyte imbalance that leads to fluid influx and cell swelling.

View Article and Find Full Text PDF