Publications by authors named "Hossein M Vardanjani"

Background: Altered thyroid function has been linked to insulin resistance (IR), but its relationship with the Metabolic Score for Insulin Resistance (METS-IR), a novel non-insulin-based index of IR, remains unclear. This study aimed to investigate the association between thyroid function status and METS-IR in a U.S.

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  • - The study assesses medication use and the prevalence of potential drug-drug interactions (pDDIs) and polypharmacy in over 9,000 post-percutaneous coronary intervention (PCI) patients in Shiraz, Iran, highlighting significant clinical challenges.
  • - Results showed that a high percentage of patients were on statins (91.6%) and antiplatelet therapy (94.5%), with 82.8% facing at least one pDDI, particularly between common medications like aspirin and clopidogrel, and 73.6% experiencing polypharmacy.
  • - The findings indicate a concerning gap between clinical guidelines and actual medication practices, urging improvements in drug interaction databases and collaboration among healthcare professionals to enhance
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Identifying COVID-19 patients' clinical phenotypes based on characteristics and comorbidities, as well as their differences, helps in terms of clinical care and potential crises. Our goal is to use Latent Class Analysis (LCA) to identify COVID-19 patient profiles based on demographics, symptoms, and comorbidities, and evaluate their correlation with ICU admission, hospitalization duration, and mortality in a cross-sectional study. We included hospitalized patients with positive SARS-CoV-2 tests in two referral hospitals in the south of Iran between January 2020 and July 2021.

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Background: The utilization of complementary and alternative medicine (CAM) is experiencing a global surge, accompanied by the adoption of national CAM policies in numerous countries. Traditional Persian medicine (TPM) is highly used as CAM in Iran, and the ongoing scientific evaluation of its interventions and the implementation of evidence-based medicine (EBM) encounters various barriers. Therefore, comprehending the characteristics and interactions of stakeholders is pivotal in advancing EBM within TPM policies.

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  • A study was conducted using data from 968,738 adults across 20 cohort studies in Asia to investigate the link between diabetes and liver cancer incidence and mortality.
  • The findings revealed that adults with diabetes had a significantly higher risk of being diagnosed with liver cancer (hazard ratio of 1.97) and dying from it (adjusted hazard ratio of 1.97) compared to those without diabetes.
  • The robust results, supported by a two-stage meta-analysis, contribute valuable evidence to the understanding of liver cancer risks among diabetic populations in Asian countries.
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  • * The study followed the PRISMA-ScR checklist, extracting data from 197 relevant papers published from 2000 to 2022, and categorized the reasons for euthanasia requests along with contextual factors like legality and human development index.
  • * Findings revealed that the most common conditions leading to euthanasia requests included terminal cancer (45.4%), Alzheimer's and dementia (19.8%), severe physical or mental suffering (19.8%), treatment-resistant mood disorders (12.2%), and advanced cardiovascular diseases (12.
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Background: Gender inequality may be associated with the burden of orofacial clefts (OFCs), particularly in low-and middle-income countries (LMICs). To investigate the OFCs' burden and its association with gender inequality in the Eastern Mediterranean region (EMR).

Methods: Country-specific data on the OFCs' prevalence and Disability-Adjusted Life Years (DALYs) from 1990 to 2019 were gathered from the Global Burden of Disease database by age and gender.

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The efficacy of botulinum toxin injection for the treatment of third, fourth, and sixth nerve palsy was evaluated. PubMed, Scopus, EMBASE, Web of Science, and Google Scholar databases were searched. Data about the duration of palsy (acute vs chronic), cause of the palsy, type of toxin used, mean dose, and other background characteristics were collected.

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  • Telomeres, which protect chromosomes, are found to be shorter in infants whose mothers experience higher psychological stress during pregnancy, suggesting potential health implications.
  • A systematic review analyzed multiple studies to understand the relationship between maternal stress and newborn telomere length (TL), confirming that increased stress correlates with decreased TL in infants.
  • The findings highlight the significant impact of maternal psychological factors on newborn health, indicating that stress during pregnancy can negatively influence telomere length, which may affect long-term health outcomes.
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Background: Gastroesophageal Reflux Disease (GERD) is a common chronic condition. Its chronic nature may affect the pattern of medication use. This study aimed to investigate the prevalence, associated factors, and patterns of polypharmacy and medication use among GERD patients in southwestern Iran.

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Aims: Heart failure (HF) is a major public health challenge. Malnutrition has a significant effect on HF prognosis. Understanding the impact of social and clinical factors on the risk of malnutrition is necessary because it may aid in improving the health status of HF patients.

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  • Age-related Macular Degeneration (AMD) is a significant cause of vision loss, particularly in aging populations, and this study focused on its prevalence among Iranians.
  • Analysis of 17 studies revealed an overall AMD prevalence of 10.8% in males and 9.8% in females, with rates increasing significantly with age, particularly in those 80 and older.
  • The study highlights a concerning trend of rising AMD cases in Iran, predicting nearly 5.5 million cases by 2050, emphasizing the need for preventive and screening strategies to manage the expected burden.
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The novel coronavirus disease 2019 (COVID-19) has had various financial and life impacts on the world's population. Schools' regular activity and function during the pandemic require balancing the repercussions of suspending in-person education versus health threats. Furthermore, children are one of the prominent victims of the restricted quarantine strategies' effects, which may make them vulnerable to various mental health problems.

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Purpose: The purpose of this study was to investigate the prevalence of cataracts, refractive disorders, age-related macular disease (AMD), and glaucoma, as well as their trends from 1990 to 2019 in Iran, in comparison with high-middle socio-demographic index (HMSDI) countries and the world, using the Global Burden of Disease (GBD) 2019 study.

Methods: The GBD study provided data on the prevalence of blindness and visual impairment (VI), as well as four of their causes including cataracts, refractive disorders, age-related macular disease (AMD), and glaucoma. Using Joinpoint analysis, the annual percent change (APC) was calculated to assess the trend of change in prevalence in each category of diseases from 1990 to 2019, stratified by sex and age, for Iran, HMSDI countries, and the world.

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Background: Some residents of the Persian Gulf Coastline (PGC) areas are circular migrants due to geo-commercial issues. They have a higher risk of HIV infection and non-disclosure of their HIV/AIDS status. These people who live with HIV (PLHIV) are considered as the bridge population for HIV transmission to general population, especially adolescents.

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Background: Women are known to use Complementary and Alternative Medicine (CAM) during pregnancy despite the subsequent potential unknown effects associated with its use. This study was performed to evaluate the use of CAM products and its related factors among pregnant women in Shiraz, Iran.

Materials And Methods: This cross-sectional study of 365 pregnant women referred to obstetrics clinics affiliated to Shiraz University of Medical Sciences (Iran) was conducted in 2020.

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Introduction: Girls can use their mother's emotional, informational and behavioral support to perform healthy behaviors due to their constant access to their mothers. This study aimed to evaluate the effect of role modeling and maternal support in the family to improve healthy behaviors and perceived Family Health Climate (FHC) in female students.

Methods: In this educational quasi-experimental study, 261 female students (133 in the intervention group and 128 in the control group) and 223 mothers (109 intervention and 114 control) were selected using the cluster multi-stages sampling method and entered the study.

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Background: Intimate partner violence (IPV) against pregnant women can cause several complications for the mother and her baby, which are life-threatening. Thus, we aimed to find the prevalence of IPV and its associated factors in pregnant women in Shiraz, Iran.

Methods: This cross-sectional study was conducted among pregnant mothers in Shiraz between July 2020 and January 2021.

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Objective: This study aimed to determine the quality of life (QOL), in patients with endometriosis ± infertility (B and C groups) and compare those to healthy women, and also infertile groups without endometriosis as a control groups (A and D), considering the fact that endometriosis and infertility reduces the quality of life in patients.

Methods: The present prospective comparative study was carried out between January 2018 and September 2020. A total of 400 women were included (100 women in each group).

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Background: Due to the rapid advancement of medical knowledge, promotion in research is necessary to have the best clinical practice. Research Self-efficacy (RSE) is the researcher's confidence in their ability to conduct a specific study. The Evidence-Based Practice (EBP) represents how to improve the quality of care and treatment of patients.

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Background: Inappropriate medication use among individuals with depressive disorders (DD) is a rising public health challenge. We aimed to investigate the polypharmacy and its determinants among individuals with DD in a less developed region, and evaluate the pattern of medication use in this population.

Methods: Data was extracted from Pars Cohort Study (PCS) between 2016 and 2019.

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Background: Kawasaki Disease (KD) is the most common childhood vasculitis and cause of acquired heart disease for no apparent reason. There is some evidence indicating infectious agents as possible triggers for KD. During the COVID-19 pandemic, vasculitis has been a presentation of COVID-19 in children.

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Background: Gastrointestinal cancers account for a significant number of deaths and new cancer cases worldwide. Our aim is to investigate stratum-specific incidence trends of esophageal cancer in southern Iran considering age, gender, and morphological (adenocarcinoma/squamous cell carcinoma) subtypes.

Method: We used data on esophageal cancer incidence in the catchment area of Shiraz Population-Based Cancer Registry.

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Background: Gastric Cancer (GC) is still one of the major causes of cancer mortality. Due to health-related transitions, the epidemiology of GC subtypes may change. These changes may have profound effects on clinical approaches as well as on public health management of GC.

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