Endocytic proteins with prion-like domains form viscoelastic condensates that enable membrane remodeling.

Membrane invagination and vesicle formation are key steps in endocytosis and cellular trafficking. Here, we show that endocytic coat proteins with prion-like domains (PLDs) form hemispherical puncta in the budding yeast, These puncta have the hallmarks of biomolecular condensates and organize proteins at the membrane for actin-dependent endocytosis. They also enable membrane remodeling to drive actin-independent endocytosis.

Fuzzy logic based classification and assessment of pathological voice signals.

In this paper an efficient fuzzy wavelet packet (WP) based feature extraction method and fuzzy logic based disorder assessment technique were used to investigate voice signals of patients suffering from unilateral vocal fold paralysis (UVFP). Mother wavelet function of tenth order Daubechies (d10) was employed to decompose signals in 5 levels. Next, WP coefficients were used to measure energy and Shannon entropy features at different spectral sub-bands.

Optimal feature selection for the assessment of vocal fold disorders.

Unilateral vocal fold paralysis, vocal fold polyp, and vocal fold nodules are the most common types of neurogenic and organic vocal disorders. This article aims to distinguish these types of vocal diseases into four different classes for the purpose of automatic screening. Firstly, the reconstructed signal at each wavelet packet decomposition sub-band in five levels of decomposition with mother wavelet of (db10) is used to extract the nonlinear features of self-similarity and approximate entropy.