Publications by authors named "Hossein Dehghani Mohammad Abadi"
Background: The most challenging risk of mechanical valves is thromboembolic events; therefore, life-long anticoagulation therapy is necessary. Anticoagulation therapy should be adjusted for each patient with serial international normalized ratio (INR) monitoring. Due to the small number of patients with a mechanical valve in the pulmonary position, we are facing a lack of information about the therapeutic range of the INR in these patients.
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- Mechanical tricuspid valve (TV) thrombosis has high incidence rates and can increase morbidity and mortality if not treated properly, prompting this study on managing patients with the condition.
- The study observed 42 patients over 11 years, noting that the majority were female, with various treatments utilized: thrombolytic therapy in 61.1%, anticoagulant adjustments in 23.9%, and surgery in 14.9%, showing different outcomes over time.
- Results indicated that while the survival rates were relatively high, recurrent thrombosis requiring further intervention was common, emphasizing the need for personalized treatment and careful monitoring of patients with mechanical TV.
Objectives: Very few reports have described the Doppler-derived echocardiographic parameters for mechanical pulmonary valve prosthesis (MPVP). This study aims to describe the normal Doppler hemodynamic profile of MPVP using Doppler echocardiography.
Methods: The current prospective, single center observational study enrolled 108 patients who underwent pulmonary valve replacement (PVR) surgery for the first time and had a normally functioning prosthesis post-operation.
Article Synopsis
- Constrictive physiology can develop after open-heart surgery, possibly leading to constrictive pericarditis, a rare but serious complication, and colchicine is thought to help prevent this condition.
- A randomized double-blind trial evaluated the effects of colchicine, comparing 1 mg once daily before surgery and 0.5 mg twice daily for 5 days after among 160 patients.
- Results showed a reduction in constrictive physiology incidence after 4 weeks for those on colchicine (11%) compared to placebo (23%), indicating that colchicine may offer preventive benefits over a longer term post-surgery.