Publications by authors named "Hossam M Abdel Wahab"
Common warts are benign skin lesions caused by the human papillomavirus. Although they are usually not harmful, they can cause pain, depending on their location. While many modalities are available for treatment of warts, none is a gold standard, and many are not affordable and/or have suboptimal outcomes.
View Article and Find Full Text PDFRetinoids and active vitamin D analogues regulate the proliferation and differentiation of keratinocytes. Retinoids are the main stay in the treatment of acne vulgaris through their comedolytic and anti-inflammatory effects. However, the effect of calcipotriol on the different forms of acne lesions has not been reported.
View Article and Find Full Text PDFArticle Synopsis
- Pityriasis alba (PA) is a skin condition that causes noticeable hypopigmentation, particularly affecting individuals with darker skin and often causing cosmetic concerns.
- The study evaluated the effectiveness of three affordable treatments for PA in comparison to a placebo over eight weeks with 80 patients participating.
- Results indicated that all treatments showed significant improvement in symptoms, with Tacrolimus 0.03% ointment being the most effective for repigmentation, although the topical corticosteroid was rated highest in patient satisfaction.
Forehead wrinkles: a histological and immunohistochemical evaluation.
J Cosmet Dermatol
September 2014
Background: Wrinkles are associated with cutaneous aging especially on sun-exposed skin. Despite they are considered a major topic in cosmetic dermatology, very few reports have studied the specific histological and immunohistochemical changes characteristic for wrinkles.
Aim: The study aims to evaluate the histological and immunohistochemical changes of static forehead wrinkles in relation to surrounding photoaged skin.
Evaluation of apoptosis regulatory proteins in response to PUVA therapy for psoriasis.
Photodermatol Photoimmunol Photomed
February 2013
Background: The histopathologic changes characteristic of psoriasis might be related to suppressed apoptosis. One of the actions of psoralen ultraviolet A (PUVA) in psoriasis could be exerted through induction of apoptosis of keratinocytes and lymphocytes; however, its exact molecular mechanism is still confusing.
Aim: In this study, we evaluated the expression of pro-apoptotic (P53, Fas and Bax) and anti-apoptotic (Bcl-2) proteins correlating it with apoptotic index (AI) and epidermal thickness in psoriatic skin before and after PUVA therapy.
Background: p53 overexpression has been reported in photoaged skin. Meanwhile, p53 gene mutations have been implicated as an important factor in the pathogenesis of ultraviolet (UV) light-induced skin cancer.
Objective: The objective was to evaluate the effect of laser resurfacing on the epidermal thickness and expression of p53 in photoaged skin.