Recognition of atomic-level difference in porphyrin dyads for self-sorted supramolecular polymer growth.

Porphyrin dyads (PDMs, where M = Zn and Cu) composed of diphenylporphyrin and tetraphenylporphyrin units, designated as DPDMs and TPDMs, respectively, exhibited remarkable differences in the molecular assemblies depending on the coordination metal ion. Furthermore, TPDMs showed self-sorting behavior during the formation of supramolecular assemblies through the recognition of atomic-level difference.

Porphyrin-based supramolecular polymers.

Porphyrin derivatives are ubiquitous in bio-organisms and are associated with proteins that play important biological roles, such as oxygen transport, photosynthesis, and catalysis. Porphyrins are very fascinating research objects for chemists, physicists, and biologists owing to their versatile chemical and physical properties. Porphyrin derivatives are actively used in various fields, such as molecular recognition, energy conversion, sensors, biomedicine, and catalysts.

Bioinspired Applications of Porphyrin Derivatives.

Porphyrin derivatives are ubiquitous in nature and have important biological roles, such as in light harvesting, oxygen transport, and catalysis. Owing to their intrinsic π-conjugated structure, porphyrin derivatives exhibit characteristic photophysical and electrochemical properties. In biological systems, porphyrin derivatives are associated with various protein molecules through noncovalent interactions.

Enhancement of Energy Transfer Efficiency with Structural Control of Multichromophore Light-Harvesting Assembly.

Multichromophore systems (MCSs) are envisioned as building blocks of molecular optoelectronic devices. While it is important to understand the characteristics of energy transfer in MCSs, the effect of multiple donors on energy transfer has not been understood completely, mainly due to the lack of a platform to investigate such an effect systematically. Here, a systematic study on how the number of donors ( ) and interchromophore distances affect the efficiency of energy transfer ( ) is presented.

Bacterial Lectin-Targeting Glycoconjugates for Selective Elimination of Pathogenic Bacteria.

Herein we report a strategy to eradicate pathogenic bacteria selectively, which utilizes bacterial lectin-targeting glycoconjugates that contain an epitope or a photosensitizer to promote antibody-dependent cellular cytotoxicity (ADCC) or photodynamic therapy (PDT), respectively. Our results show that death promoted by using the designed synthetic glycoconjugates coupled with ADCC or PDT takes place selectively in pathogenic bacteria expressing lectins on their surfaces.

Cancer cell death using metabolic glycan labelling techniques.

Herein we describe a method for inducing cancer cell death, which relies on the use of a H2O2-responsive glycan metabolic precursor in conjunction with antibody-dependent cellular cytotoxicity (ADCC) or photodynamic therapy (PDT).

Metal-organic framework based on hinged cube tessellation as transformable mechanical metamaterial.

Mechanical metamaterials exhibit unusual properties, such as negative Poisson's ratio, which are difficult to achieve in conventional materials. Rational design of mechanical metamaterials at the microscale is becoming popular partly because of the advance in three-dimensional printing technologies. However, incorporating movable building blocks inside solids, thereby enabling us to manipulate mechanical movement at the molecular scale, has been a difficult task.

Hierarchical Hybrid Nanostructures Constructed by Fullerene and Molecular Tweezer.

For the construction of well-defined hierarchical superstructures of pristine [60]fullerene (C) arrays, pyrene-based molecular tweezers (PT) were used as host molecules for catching and arranging C guest molecules. The formation of host-guest complexes was systematically studied in solution as well as in the solid state. Two-dimensional proton nuclear magnetic resonance spectroscopic studies revealed that PT-host and C-guest complexes were closely related to the molecular self-assembly of PT.

Supramolecular coordination polymer formed from artificial light-harvesting dendrimer.

We report the formation of supramolecular coordination polymers formed from multiporphyrin dendrimers (PZnPM; M = FB or Cu), composed of the focal freebase porphyrin (PFB) or cupper porphyrin (PCu) with eight zinc porphyrin (PZn) wings, and multipyridyl porphyrins (PyPM; M = FB or Cu), PFB or PCu with eight pyridyl groups, through multiple axial coordination interactions of pyridyl groups to PZns. UV-vis absorption spectra were recorded upon titration of PyPFB to PZnPFB. Differential spectra, obtained by subtracting the absorption of PZnPFB without guest addition as well as the absorption of PyPFB, exhibited clear isosbestic points with saturation binding at 1 equiv addition of PyPFB to PZnPFB.