Minimal inhibitory concentration (MIC) of caspofungin and itraconazole inhibiting growth of Candida strains calculated from the linear regression equation.

Purpose: The aim of the study was to compare the susceptibility of Candida species to caspofungin and itraconazole.

Material And Methods: 118 strains of Candida species were used in the study: 8 pattern strains and 110 strains isolated from different ontocenoses. The susceptibility of fungi strains to drugs was determined by diffusion in agar gel.

[Susceptibility to itraconazole and miconazole of fungi strains isolated from the vaginal ontocenosis].

The activity of itraconazole (RO 51211, molecular weight 705,64) and miconazole (RO 14889, molecular weight 479,15) obtained from Janssen Pharmaceutica NV, against 100 fungi strains, was studied. These strains were isolated from vaginal materials of patients with recognized candidosis. The axenic fungal strains were assessed by own methods and unified tests (bioMérieux: API 20 C, API 20 C AUX).

[The sensitivity to ketoconazole of Candida strains isolated from the digestive tract ontocenoses in children].

The study included 52 children. During endoscopy the contents of oesophagus, stomach and duodenum were collected with catheters, and additionally washings from the oral cavity and anal swabs or samples of faeces. Materials were inoculated on Sabouraud's media.

[The comparison of susceptibility of Candida albicans and Candida glabrata to miconazole].

Candida glabrata is very important pathogen which is resistant to some imidazoles (fluconazole). The aim of study was to compare a susceptibility of Candida albicans and Candida glabrata - strains isolated from patietnts treated in Centre for Treatment of Parasitic Diseases and Mycoses - to miconazole using MIC. 96.