Medical Biomonitoring of Maternal and Fetal Exposure to Carbon Monoxide and its Modification by Demographic and Obstetric Characteristics.

Background: There is a paucity of organized human biomonitoring, including that of carbon monoxide (CO) in the Niger Delta, Nigeria. The study aims to quantify the impact of maternal exposure to CO in the first trimester of pregnancy and its modification by maternal demographic and obstetric factors.

Methodology: It was of cross-sectional design conducted at the Rivers State University Teaching Hospital (RSUTH) in Nigeria.

The Case for Early and Universal Screening for Gestational Diabetes Mellitus: Findings from 9314 Pregnant Women in a Major City in Nigeria.

Introduction: Risk-based screening has been replaced by universal screening as the recommended course of care for gestational diabetes mellitus (GDM). As of 2016, no state in Nigeria had implemented a policy of universal screening for GDM. This research aimed to assess findings from a universal screening programme and its implication for scaling up universal and early screening for GDM.

Endrin resistance in the pine mouse.

Wild pine mice with a history of treatment with endrin exhibited a 12-fold greater tolerance to the pesticide than did mice having no history of endrin treatment. A genetic basis for the resistance would be expected, in view of the fact that the resistant mice had been exposed to endrin for 11 years. However, sublethal dosages conferred a degree of resistance on both mouse populations; this indicates the possibility of an inducible resistance.

CURRENT CONCEPTS OF CANCER.

Because the cancerous change in cells appears to be a permanent alteration, handed on to daughter cells through innumerable divisions, it seems probable that it reflects an abnormality in the transfer of information from cell to daughter cells. Transfer of information in cells is believed to depend on their genetic apparatus, and transfer of abnormal information implies that the genetic apparatus is not functioning normally. Abnormalities in genetic material, whether induced by ionizing radiation, chemical compounds or viruses, would, if reproduced at cell division, reappear in daughter cells.