A fish scale-derived collagen matrix as artificial cornea in rats: properties and potential.

Purpose: A fish scale-derived collagen matrix (FSCM) is proposed as an alternative for human donor corneal tissue. Light scatter and light transmission of the FSCM were measured and compared with human cornea, and its short-term biocompatibility was tested in a rat model.

Methods: light scatter was determined with a straylight measuring device, whereas light transmission was measured using a broadband absorption spectrometer.