Relationship of macromolecular synthesis to competence induction in a group H streptococcus.

Group H streptococcus strain Wicky, which was induced to competence for genetic transformation with competence factor (CF) derived from a related strain, displayed reduced rates of ribonucleic acid (RNA) and peptidoglycan synthesis. Pulse-labeling studies revealed that the inhibition of both RNA and peptidoglycan synthesis was maximal at the peak of competence and decreased as competence declined. These studies indicated that competence induction had only a slight effect on the rate of protein synthesis.

Effect of competence induction on macromolecular synthesis in a group H streptococcus.

The effects of competence induction by competence factor (CF) on macromolecular synthesis in group H streptococcus strain Wicky were investigated. CF preparations (culture filtrates from competent group H streptococcus strain Challis) were either heated or partially purified to remove a bacteriocin. These preparations did not inhibit growth, although they induced high levels of competence in strain Wicky.

Sensorimotor control in Parkinsonism.

Performance on two sensorimotor tasks was compared between 28 patients with Parkinsonism and 28 age and sex matched controls. One task involved complex motor activity (the Bead and Tapper test) and the other simple motor activity with a verbal component (the Letter Cancellation test). Both tests had three levels of complexity.

Huntington's chorea and tryptophan.

Daily use of 7 g l-tryptophan and 70 mg pyridoxine for 14 days led to no deterioration of objectively measured manual motor skills in a small group of patients with Huntington's chorea.

Unilateral electroconvulsive therapy and cerebral dominance: effect of right- and left-sided electrode placement on verbal memory.

Unilateral electroconvulsive therapy was given to 32 right-handed patients for relief of depression. Sixteen patients received electrode placement on the right side for the first treatment and on the left side for the second treatment. For the other 16 patients the order of sides was reversed.

Chromatographic Validation of Two Morphologically Similar Hybrids of Different Origins.

The origin of natural hybrids of the plant Baptisia was determined by chromatographic analyses of leaf extracts of both hybrid and parent plants. This method demonstrated a pattern of inheritance in the hybrid of certain species specific components of both parents.