A Novel Homozygous Frameshift Mutation in Exon 2 of Gene Associated with Severe Obesity: A Case Report.

Background: Monogenic obesity is a rare type of obesity caused by a mutation in a single gene. Patients with monogenic obesity may develop early onset of obesity and severe metabolic abnormalities.

Case Presentation: A two-and-half-year-old girl was presented to our clinic because of excessive weight gain and hyperphagia.