Human papillomavirus DNA and oncogene alterations in colorectal tumors.

The aim of the present study is to determine the presence and molecular integrity of high-risk HPV types in colorectal adenocarcinomas and to assess whether viral DNA is related to common proto-oncogene alterations, such as k-ras mutations and c-myc gene amplification, in colorectal cancer. Seventy-five colorectal adenocarcinomas were screened for HPV infection using nested-PCR (MY09/11-GP5+/6+). HPV typing was performed by type-specific PCR for HPV 16 and HPV 18 DNA.

["Glassy - cell" like adenocarcinoma: a new variant of gastric tumor].

Most gastric malignancies correspond histologically to adenocarcinomas, either of the intestinal or diffuse type, other tumoral varieties being much less frequent. We report a case of a malignant epithelial tumor, whose histological and cytological characteristics correspond to an unusual, although well defined entity, which may appear in the cervix and less frequently in the endometrium, known as adenocarcinoma of the glassy - cell variety. We have not found any previous reports of this particular.

[Epidermoid carcinoma of gallbladder: analysis of our casuistic].

Background: The most common type of gallbladder cancer is the adenocarcinoma. The squamous cell carcinoma represents only a 0-12% of all gallbladder tumors.

Methods: 124 cases of malignant neoplasias of the gallbladder were diagnosed during the last 33 years in the Department of Surgery of our hospital.

[Lymphoepithelioma-like gastric carcinoma: unusual variant in postgastrectomy stump].

Gastric lymphoepithelioma--like carcinoma, undifferentiated with lymphoid or medullary stroma, constitutes a 3.8% of gastric carcinomas. Microscopically it is similar to other lymphoepitheliomas, it has an expansive growth and better prognosis than other histologic types.