Ropinirole in Bipolar Disorder: Rate of Manic Switching and Change in Disease Severity.

Purpose: To determine the effects of ropinirole on manic switching and disease severity in bipolar disorder.

Design And Methods: A cross-sectional survey was conducted in 23 bipolar depressed patients using ropinirole combination therapy (Young Mania Rating Scale [YMRS], Bipolar Inventory of Symptoms Scale [BISS]). Retrospective Clinical Global Impression of Change (CGI-C) and CGI-S (Severity) were captured via chart review.

Neuroimaging in psychiatry.

Psychiatric neuroimaging has made great strides. PET scanning to differentiate between the dementias is clinically useful and well accepted. Understanding of the pathophysiology underlying the psychopathology of psychiatric illness also is rapidly expanding.