Publications by authors named "Hoon S Khoo-Tan"
Objective: The use of adjuvant radiotherapy for early stage node negative patients varies for different institutions. The recognized factors such as deep stromal invasion, lymph vascular space invasion, and size of tumor are the most common factors cited for adjuvant radiotherapy. Studies done have shown that this increases local control but may increase chronic toxicity rates.
View Article and Find Full Text PDFObjective: It is our standard of care to include pelvic lymph node dissection (PLND) in the staging of endometrial cancer, followed by adjuvant vaginal vault brachytherapy. We report our experience and outcome of patients with stage 1C grade 3 endometrial cancer from KK Hospital Singapore.
Methods: Records of patients with a diagnosis of stage 1C grade 3 endometrial cancer (based on the 1988 FIGO [International Federation of Gynecology and Obstetrics] staging system) from 1995 to 2008 were retrospectively reviewed.
Article Synopsis
- This study analyzed the survival outcomes and failure patterns in 120 patients with locally advanced cervical cancer treated with high-dose rate brachytherapy and cisplatin-based chemoradiotherapy from 1999 to 2005.
- The 5-year overall survival rate was 65%, while the disease-free survival rate was 57.3%, with most recurrences occurring at distant sites.
- Significant factors impacting survival included low hemoglobin levels and tumor size, highlighting the need for further research on the safety of this treatment combination and the importance of imaging for assessing prognosis.