Oxyanion-Sensitive Catalytic Activity of Ni(II)/Oxyanion Systems for Heterogeneous Organic Degradation: Differential Oxidizing Capacity of Ni(III) and Ni(IV) as High-Valent Intermediates.

This study demonstrated that NiO and Ni(OH) as Ni(II) catalysts exhibited significant activity for organic oxidation in the presence of various oxyanions, such as hypochlorous acid (HOCl), peroxymonosulfate (PMS), and peroxydisulfate (PDS), which markedly contrasted with Co-based counterparts exclusively activating PMS to yield sulfate radicals. The oxidizing capacity of the Ni catalyst/oxyanion varied depending on the oxyanion type. Ni catalyst/PMS (or HOCl) degraded a broad spectrum of organics, whereas PDS enabled selective phenol oxidation.

Novel Noise Injection Scheme to Guarantee Zero Secrecy Outage under Imperfect CSI.

The paper proposes a novel artificial noise (AN) injection strategy in multiple-input single-output multiple-antenna-eavesdropper (MISOME) systems under imperfect channel estimation at the legitimate channel to achieve zero secrecy outage probability under any circumstance. The zero secrecy outage is proved to always be achievable regardless of the eavesdropper's number of antennas or location when the pair secrecy and codeword rates are chosen properly. The results show that when there is perfect channel state information, the zero-outage secrecy throughput increases with the transmit power, which is important for secrecy design.

Non-canonical MLL1 activity regulates centromeric phase separation and genome stability.

Epigenetic dysregulation is a prominent feature in cancer, as exemplified by frequent mutations in chromatin regulators, including the MLL/KMT2 family of histone methyltransferases. Although MLL1/KMT2A activity on H3K4 methylation is well documented, their non-canonical activities remain mostly unexplored. Here we show that MLL1/KMT2A methylates Borealin K143 in the intrinsically disordered region essential for liquid-liquid phase separation of the chromosome passenger complex (CPC).

Design and Implementation of a Multi-Hop Real-Time LoRa Protocol for Dynamic LoRa Networks.

Recently, LoRa (Long Range) technology has been drawing attention in various applications due to its long communication range and high link reliability. However, in industrial environments, these advantages are often compromised by factors such as node mobility, signal attenuation due to various obstacles, and link instability due to external signal interference. In this paper, we propose a new multi-hop LoRa protocol that can provide high reliability for data transmission by overcoming those factors in dynamic LoRa networks.

Revisiting the Oxidizing Capacity of the Periodate-HO Mixture: Identification of the Primary Oxidants and Their Formation Mechanisms.

This study reexamined the mechanisms for oxidative organic degradation by the binary mixture of periodate and HO (PI/HO) that was recently identified as a new advanced oxidation process. Our findings conflicted with the previous claims that (i) hydroxyl radical (OH) and singlet oxygen (O) contributed as the primary oxidants, and (ii) OH production resulted from HO reduction by superoxide radical anion (O). PI/HO exhibited substantial oxidizing capacity at pH < 5, decomposing organics predominantly by OH.

Site-specific covalent labeling of His-tag fused proteins with N-acyl-N-alkyl sulfonamide reagent.

The ability to incorporate a desired functionality into proteins of interest in a site-specific manner can provide powerful tools for investigating biological systems and creating therapeutic conjugates. However, there are not any universal methods that can be applied to all proteins, and it is thus important to explore the chemical strategy for protein modification. In this paper, we developed a new reactive peptide tag/probe pair system for site-specific covalent protein labeling.

Methylation of the NT5E Gene Is Associated with Poor Prognostic Factors in Breast Cancer.

Cluster of differentiation (CD) 73, which is encoded by the gene, regulates production of immunosuppressive adenosine and is an emerging checkpoint in cancer immunotherapy. Despite the significance of CD73 in immuno-oncology, the roles of the gene methylation in breast cancer have not been well-defined yet. Therefore, we aimed to investigate the prognostic significance of the gene methylation in breast cancer.

Expression of CD73 is associated with tumor progression and intratumoral inflammation in breast cancer.

CD73 is a lymphocyte differentiation antigen and highly expressed in many human solid tumors. CD73 is known to be associated with tumor progression, but its role in human breast cancer is still under investigation. The aims of this study were to evaluate the expression of CD73 in human breast cancer and to analyze its prognostic significance in breast cancer.

Reverse Warburg Effect-Related Mitochondrial Activity and F-FDG Uptake in Invasive Ductal Carcinoma.

Purpose: We evaluated the relationship between fluorine-18 fluoro-2-deoxy-glucose (F-FDG) uptake and mitochondrial activity in cancer cells and investigated the prognostic implications of this relationship in patients with invasive ductal carcinoma of the breast (IDCB).

Methods: One hundred forty-six patients with primary IDCB who underwent preoperative F-FDG PET/CT followed by curative surgical resection were enrolled in the current study. Mitochondrial activity of cancer cells was assessed based on translocase of outer mitochondrial membrane 20 (TOMM20) expression and cytochrome C oxidase (COX) activity.

X-rays and scans can fail to differentiate hip pathology from lumbar spinal stenosis: Two case reports.

Background: Occasionally, hip pathologies may present alone or combined with lumbar spine pathology, especially lumbar stenosis. Although the history and clinical examination may help differentiate between the two, hip X-rays alone without accompanying magnetic resonance imaging (MRI) studies may prove unreliable.

Case Descriptions: Case 1 - A 72-year-old male presented with the sudden onset of severe back and left posterior thigh pain.

Methylation of the Gene is Associated with Expression of NF-κB1 in Response to TNF-α in Breast Cancer.

The nuclear factor (NF)-κB family of transcriptional factors plays a critical role in inflammation, immunoregulation, cell differentiation, and tumorigenesis. This study aims to investigate the role of methylation of genes encoding for the NF-κB family in breast cancer. We analyze the DNA methylation status of the gene and the gene in breast cancer using pyrosequencing.

Evaluation of the plan delivery accuracy of intensity-modulated radiation therapy by texture analysis using fluence maps.

Purpose: The aim of this study is to evaluate the plan delivery accuracy of intensity-modulated radiation therapy (IMRT) by using textural features calculated from fluence maps.

Methods: In total, 202 IMRT plans were generated with the Trilogy (C-series linac) and TrueBeam STx systems. Fluence maps were obtained for each IMRT plan.

An Energy-Efficien Slotted Sense Multiple Access Broadcast Protocol for Reliable Command Delivery in Dynamic Wireless Sensor Networks.

In industrial monitoring and control applications, a server often has to send a command to a node or group of nodes in wireless sensor networks. Flooding achieves high reliability of message delivery by allowing nodes to take the redundancy of receiving the identical message multiple times. However, nodes consume much energy due to this redundancy and the long duty cycle.

Significance of Intratumoral Fibrosis in Clear Cell Renal Cell Carcinoma.

Background: Intratumoral fibrosis (ITF) is a frequent histologic finding in solid organ tumors. Renal cell carcinoma (RCC) is a highly vascularized tumor with different shapes and degrees of ITF and inflammation. ITF is a poor prognostic factor, especially in breast cancer, and is related to intratumoral necrosis (ITN) and intratumoral inflammation (ITI).

Association between lysyl oxidase and fibrotic focus in relation with inflammation in breast cancer.

We hypothesized that lysyl oxidase (LOX) contributes to the formation of fibrotic focus (FF) in association with inflammation and serves a significant role in breast carcinogenesis. In the present study, the association between the expression of LOX family members and FF with regards to with inflammation was analyzed, and the prognostic significance of LOX and FF in breast cancer was investigated. Immunohistochemical staining for LOX, LOX-like protein (LOXL) 1, LOXL2 and LOXL3 was performed in primary breast cancer tissues.

Association between inflammation and cancer stem cell phenotype in breast cancer.

Inflammation and cancer stem cells (CSCs) are becoming increasingly recognized as components of tumorigenesis in breast cancer. In the present study, the association between inflammation and BCSC phenotype was evaluated in human breast cancer tissue. Immunohistochemical staining for cluster of differentiation (CD)24, 44, 4, 8 and 68 was performed using tissue microarray blocks containing 47 consecutive cases of invasive breast carcinoma and 10 normal breast tissue samples.

Prognostic Significance of Activated Leukocyte Cell Adhesion Molecule (ALCAM) in Association with Promoter Methylation of the ALCAM Gene in Breast Cancer.

Activated leukocyte cell adhesion molecule (ALCAM) has been implicated in tumorigenesis. In this study, we studied DNA methylation status of the gene using pyrosequencing in breast cancer tissues. We analyzed the association between the methylation status of the gene and its expression.

The structural changes of upper airway and newly developed sleep breathing disorders after surgical treatment in class III malocclusion subjects.

Bimaxillary surgery is the traditional treatment of choice for correcting class III malocclusion which is reported to cause an alteration of oropharyngeal structures and upper airway narrowing that might be a predisposing factor for obstructive sleep apnea (OSA). This study aimed to analyze sleep parameters in class III malocclusion subjects and ascertain the prevalence of snoring or OSA following bimaxillary surgery.A total of 22 patients with Le Fort I osteotomy and mandibular setback for class III malocclusion were prospectively enrolled.

Optimized Sharable-Slot Allocation Using Multiple Channels to Reduce Data-Gathering Delay in Wireless Sensor Networks.

The demand for event-driven real-time applications for timely and reliable data acquisition is growing in industrial sectors. However, it is challenging to satisfy the requirements since constraints such as limited available energy and bandwidth are inherent in a wireless sensor network. To deal with timely delivery, one desirable approach is to improve network throughput so that more real-time applications with tighter time constraints can be satisfied in any given network.

Is Radiologic Evaluation Necessary to Find out Foreign Bodies in Nasal Cavity?

Although there were previous studies on the clinical aspects such as etiology, treatment modalities, studies regarding the necessity of radiologic evaluation for nasal foreign body were limited. The aim of this study is to evaluate the necessity and indication of radiologic evaluation for nasal foreign bodies. There are consecutive patients aged less than 10 years who presented with suspected foreign bodies in nasal cavity.

A case of hepatoblastoma misdiagnosed as combined hepatocellular carcinoma and cholangiocarcinoma in an adult.

Hepatoblastoma usually occurs in children under the age of 2 years, with very few cases reported in adults. We experienced a case of adult hepatoblastoma in a 36-year-old female with chronic hepatitis B. She had experienced sudden onset abdominal pain.