Publications by authors named "Honorat Gustave Marie Zoure"
Background: Over the past two decades, preventive chemotherapy (PC) with praziquantel (PZQ) is the major strategy for controlling schistosomiasis in Senegal. The objective of this analysis was to update the endemicity of schistosomiasis at community level for better targeting mass treatment with PZQ in Senegal.
Methods: Demographic and epidemiological data from 1610 community health areas were analyzed using the schistosomiasis community data analysis tool of Expanded Special Project for Elimination of Neglected Tropical Diseases which developed by World Health Organization/Africa Office (WHO/AFRO).
Elimination of an infectious disease requires subcritical transmission, or a reproductive number less than one, and can be assessed with cross-sectional surveys conducted by neglected tropical disease programs. Here, we assess the distribution of onchocerciasis prevalence taken from surveys across sub-Saharan Africa before the initiation of ivermectin in mass drug administrations. Pre-intervention nodular palpation cross-sectional surveys were available from 15 countries in the Expanded Special Project for Elimination of Neglected Tropical Diseases (ESPEN) database.
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- Loiasis poses a significant risk for ivermectin treatment in Central Africa, leading to severe adverse reactions, making accurate geographic mapping crucial.
- APOC conducted RAPLOA surveys in nearly 4800 villages across 11 countries, revealing that around 14.4 million people live in high-risk loiasis areas, with data showing strong spatial correlations.
- The study produced the first global map of loiasis based on survey data, identifying zones of hyperendemicity and areas free of loiasis, while improving understanding of the disease's distribution in several Central African nations.