Publications by authors named "Honoka Kaneko"
Anal Bioanal Chem
January 2024
Article Synopsis
- The study presents an improved method for quantifying serum/plasma estradiol (E), which is important in diagnosing and monitoring estrogen-related diseases.
- The new technique employs a quicker derivatization process using MPDNP-F and liquid chromatography/electrospray ionization-tandem mass spectrometry (LC/ESI-MS/MS), significantly reducing reaction time from 90 minutes to just 15 minutes.
- This method enhances sensitivity and specificity in measuring estradiol levels, allowing for precise detection even at low concentrations (5.0 pg/mL) using a small sample size, outperforming traditional methods like chemiluminescence enzyme immunoassays.
