Associations between genetically predicted sex and growth hormones and facial aging in the UK Biobank: a two-sample Mendelian randomization study.

Background: Aging is an inescapable process, but it can be slowed down, particularly facial aging. Sex and growth hormones have been shown to play an important role in the process of facial aging. We investigated this association further, using a two-sample Mendelian randomization study.

Investigation of retro-orbicularis oculi fat and associated orbital septum connective tissues in upper eyelid surgery.

Background: To study the anatomical characteristics of retro-orbicularis oculi fat (ROOF) in the upper eyelid and to investigate its relevance in upper eyelid surgery.

Methods: Thirty-eight Chinese hemifacial cadaver specimens were used. Several sagittal plane section planes were recorded from the medial canthus to the lateral canthus of the eyelid after P45 sheet plastination.

Osteogenically-induced exosomes stimulate osteogenesis of human adipose-derived stem cells.

Exosomes exhibit great therapeutic potential in bone tissue engineering. The study aimed to investigate whether the exosomes derived from human adipose-derived stem cells (hADSCs-Exos) during different time-span of osteogenic differentiation could promote osteogenesis. The appropriate concentrations of hADSCs-Exos to enhance the proliferation, migration and osteogenesis of hADSCs-Exos were also examined.

The Use of P45 Plastination Technique to Study the Distribution of Preseptal and Preaponeurotic Fat Tissues in Asian Eyelids.

This study evaluated the anatomical features of preseptal and preaponeurotic fat tissues in the upper eyelids of individuals of Asian heritage. Specifically, we attempted to elucidate the role of these tissues in the formation of sunken upper eyelids and devise an easy and feasible approach to rectify this. Sixteen heads (32 facial halves) from fresh adult cadavers were processed using the P45 plastination techniques.

[Anthropometric analysis of facial aging in 1200 Han adult people in Dalian].

Objective: To investigate the facial aging analysis of 1200 Han adult people in Dalian with iris diameter, so as to provide reference for facial rejuvenation in Han people.

Methods: 1200 facial digital photographs from the second-generation ID card of China were stratified randomly selected as the research sample, excluding facial deformity, tattooing eyebrow, tattooing lid margin, ptosis, lip grain and eyebrow deformity cases, as well as the cases whose join point of upper eyelid and lower eyelid not exposed at the nasal side. These photos were divided into six cohorts: female aged 18, 38, and 68 years old; and male aged 18, 38, and 68 years old, with 200 cases in each cohort.

Are There Differences Between the Upper and Lower Parts of the Superficial Musculoaponeurotic System? A Preliminary Biomechanical Study.

Background: The superficial musculoaponeurotic system (SMAS) becomes thinner and gradually disappears from the midface. In rhytidectomy, manipulation of the SMAS occurs in the lateral area, and previous research has focused primarily on the SMAS region as a whole.

Objectives: In this preliminary study, the authors compared the viscoelasticity of the upper and lower regions of the SMAS using biomechanical techniques.