Publications by authors named "Hongzhi Mi"
We present a case of a 49-year-old woman who complained of chest pain after activity for 3 months. She had undergone percutaneous coronary intervention (PCI) on the left main (LM) and right coronary artery (RCA) for acute myocardial infarction (AMI) 1 year ago. At this admission, a coronary angiogram (CAG) revealed stent restenosis.
View Article and Find Full Text PDFDiagnostic Value of Magnetocardiography to Detect Abnormal Myocardial Perfusion: A Pilot Study.
Rev Cardiovasc Med
October 2024
Article Synopsis
- - Magnetocardiography (MCG) is a new non-invasive method that detects weak magnetic fields created by the heart's electrical activity, aiming to identify issues like myocardial ischemia by comparing its results to single-photon emission computed tomography (SPECT).
- - The study involved 112 patients with chest pain who underwent both SPECT and MCG scans, and researchers used machine learning techniques (random forest, decision tree, support vector machine) to analyze data and predict impaired blood flow to the heart.
- - Five key MCG variables were found to effectively predict impaired myocardial perfusion, with the study showing high sensitivity in the machine learning models, although specificity was generally lower, highlighting MCG's potential as a valuable future tool
Tea plant (Camellia sinensis) is an important economical crop that frequently suffers from various herbicides, especially glyphosate. However, the molecular responses and regulatory mechanisms of glyphosate stress in tea plants remain poorly understood. Here, we reported a transcriptome dataset and identified large number of differentially expressed genes (DEGs) under glyphosate exposure.
View Article and Find Full Text PDFArticle Synopsis
- Inflammation from activated macrophages in vulnerable atherosclerotic plaques (VAPs) increases the risk of plaque rupture, and the translocator protein (TSPO) is crucial for detecting this inflammation.
- The study used F-FDPA radiotracers to image and quantify plaque inflammation in three groups of rabbits, finding significant differences in tracer uptake between those with VAPs and other groups.
- Results indicated that F-FDPA uptake correlated with increased macrophage presence and inflammation in atherosclerotic plaques, highlighting its potential as an effective method for assessing vascular inflammation.
Background: Mental stress-induced myocardial ischemia (MSIMI) frequently occurs in patients with coronary artery disease (CAD), and is even more common in patients with co-occurring CAD and depression/anxiety. MSIMI appears to be a poor prognostic factor for CAD, but existing data on depression/anxiety patients are limited.
Methods: This cohort study will consecutively screen 2,647 CAD patients between 2023 and 2025.
Objective: We sought to determine the association between mental stress-induced myocardial ischaemia (MSIMI) and quality of life (QoL) in patients with coronary artery disease (CAD) after coronary revascularization.
Methods: This cohort study involved patients with high-risk MSIMI who received coronary revascularization between Dec 2018 and Dec 2019. Patients who screened positive for depression/anxiety were enrolled in this study.
Viability and functional assessments are recommended for indication and intervention for chronic coronary total occlusion (CTO). We aimed to evaluate myocardial viability and left ventricular (LV) functional status by using cardiovascular magnetic resonance (CMR) and to investigate the relationship between them and collaterals in patients with CTO. We enrolled 194 patients with one CTO artery as detected by coronary angiography.
View Article and Find Full Text PDFA translocator protein 18 kDa targeted radiotracer, N,N-diethyl-2-(2-(4-[F]fluorophenyl)-5,7-dimethylpyrazolo[1,5-a] pyrimidin-3-yl) acetamide ([F]FDPA), was automated synthetized and evaluated for cardiac inflammation imaging. Various reaction conditions for an automated synthesis were systematically optimized. MicroPET/CT imaging were performed on normal rats and rats with myocardial infarction (MI).
View Article and Find Full Text PDFTo compare the left ventricular (LV) phase dyssynchrony parameters obtained from Tc-99m Sestamibi SPECT (GSPECT) and F-18 FDG PET(GPET), as well as the prognostic values in patients with ischemic cardiomyopathy (ICM). Consecutive ICM patients referred for myocardial viability assessment were retrospectively evaluated and were followed-up for 21 ± 5 months. Phase parameter from both GSPECT and GPET were analyzed by QGS software, including histogram bandwidth (BW), standard deviation (SD) and entropy.
View Article and Find Full Text PDFAims: The purpose of the present trial is to determine whether opening co-existing chronic total occlusions (CTOs) using percutaneous coronary interventions (PCIs) improves cardiac function in patients with multi-vessel disease (MVD). Patients with MVD are defined as having at least one additional major vessel exhibiting no less than 75% stenosis combined with the presence of a CTO artery.
Methods And Results: Patients will be prospectively recruited who meet the following criteria:Patients presenting with no necrosis of myocardial tissue in the territory of the CTO will be excluded.
Objective: To analyze the relationship between the collateral flow of coronary chronic total occlusion (CTO) and myocardial viability detected by F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) imaging.
Methods: A prospective analysis of 104 patients diagnosed by coronary angiography. All patients underwent resting myocardial perfusion imaging and PET/CT within 1 week.
Objective: To assess the diagnostic accuracy of ventilation/perfusion (V/Q) single photon emission CT (SPECT) as compared to computed tomographic pulmonary angiography (CTPA) for pulmonary embolism (PE).
Methods: In this prospective multicenter study, 111 patients in whom acute or sub-acute PE was clinically confirmed or suspected were enrolled. The patients underwent one-day method V/Q lung scan (including SPECT and planar imaging) within 3 days before and after completion of CTPA.
Objective: Apoptosis contributes to the instability of the atherosclerotic (AS) lesions. The vulnerable plaque was identified in vivo by detecting the apoptosis with radiolabeled annexin V in an atherosclerotic rabbit model.
Methods: Eight male New Zealand white rabbits on 2% cholesterol diet for 2 weeks had abdominal aortic balloon injury and fed a 2% cholesterol diet for another 15 weeks (AS group), 3 rabbits fed a normal rabbit chow for 17 weeks without balloon injury served as controls.