Publications by authors named "Hongying Pan"

Objective: To systematically analyze the impact of pulmonary rehabilitation (PR) on postoperative recovery of lung cancer patients undergoing thoracoscopic partial pulmonary resection.

Methods: This study has been registered with PROSPERO (CRD42024574965). A comprehensive search was conducted in PubMed, The Cochrane Library, Embase, Web of Science and CINAHL for literature on the effects of PR on postoperative rehabilitation in lung cancer patients undergoing thoracoscopic partial pulmonary resection, up to May 2024.

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Background: Catheter-related bloodstream infection (CR-BSI) stands as one of the leading causes of hospital-acquired infections, often resulting in high healthcare expenditure and mortality rates. Despite efforts, reducing the incidence of CR-BSI remains a significant challenge.

Objective: This study aimed to assess the impact of a multidisciplinary organizational intervention on reducing intravenous CR-BSI.

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Article Synopsis
  • Chronic hepatitis B virus (HBV) infection remains a major health concern, especially regarding the timing of antiviral therapy.
  • This study analyzed liver histological changes in 339 treatment-naïve patients with normal alanine aminotransferase (ALT) levels, focusing on differences between HBeAg-positive and HBeAg-negative individuals.
  • Key findings showed that HBsAg and AST levels were critical for assessing liver inflammation, while HBV DNA load and age were important for evaluating liver fibrosis in patients with normal ALT levels.
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Background: The amount of prediction models for disability in older adults is increasing but the prediction performance of different models varies greatly, and the quality of prediction models is still unclear.

Objectives: To systematically review and critically appraise the studies on risk prediction models for disability in older adults.

Methods: A systematic literature search was conducted on PubMed, Embase, Web of Science, Cochrane Library, Cumulative Index to Nursing and Allied Health Literature (CINAHL), China National Knowledge Infrastructure (CNKI), China Science and Technology Journal Database (VIP), and Wanfang Database, published up until June 30, 2023.

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Purpose: To construct an index system to evaluate the competencies of nurses in enhanced recovery after surgery (ERAS) programs and provide a scientific foundation for their training and assessment.

Methods: Utilizing a literature review and semi-structured interviews, a preliminary indicator system was constructed. Based on the preliminary indicator system, a Delphi questionnaire was developed and utilized to achieve consensus among experts in two rounds of Delphi studies.

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Bariatric surgery may cause intestinal microecological environment imbalance due to changes in gastrointestinal anatomy. Some patients may have compli-cations, even regain weight. Probiotics can act on intestinal mucosa, epithelium and gut-associated lymphoid tissue to improve the intestinal microecological environment of obese patients after bariatric surgery.

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Article Synopsis
  • The study aimed to evaluate the effectiveness and tolerability of direct-acting antiviral (DAA) treatments for hepatitis C virus (HCV) across different genotypes (GTs) in a global, real-world context, focusing particularly on GT3 and GT6.
  • Researchers analyzed data from 15,849 chronic hepatitis C patients across Asia, North America, and Europe over a seven-year period, noting demographic factors such as age, sex, and prior treatment history.
  • Results showed a high sustained virological response (SVR12) rate of 96.9% overall, with variances by genotype, highlighting that independent factors like advanced age, cirrhosis, and previous treatment failures affected treatment outcomes, while being
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Background: Superior mesenteric artery (SMA) injuries rarely occur during blunt abdominal injuries, with an incidence of < 1%. The clinical manifestations mainly include abdominal hemorrhage and peritoneal irritation, which progress rapidly and are easily misdiagnosed. Quick and accurate diagnosis and timely effective treatment are greatly significant in managing emergent cases.

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This study aimed to investigate the contemporary status and influencing factors of foot self-care behavior in diabetic foot amputation patients. A total of 250 patients with diabetic foot amputation were included. The general information questionnaire, Chinese Version of the Nottingham Assessment of Function Footcare (CNAFF), Knowledge of Diabetic Foot Questionnaire, and The Third Version of the Diabetes Attitude Scale were used to investigate the status and influencing factors of foot self-care behavior in patients with diabetic foot amputation.

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  • Protothecosis is a fungal infection that can affect both immunocompromised and healthy individuals; the study focuses on its epidemiology in China.
  • A successful case of cutaneous protothecosis treated with fluconazole is reported, alongside an analysis of 29 other cases, highlighting Prototheca wickerhamii as the most common infection in the region.
  • The findings aim to improve understanding and clinical strategies for diagnosing and treating protothecosis in China, with itraconazole being the preferred treatment option.
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Background: Previous studies on the relationship between systemic lupus erythematosus (SLE) and autoimmune liver diseases (AILDs) are inconclusive. Therefore, we employed Mendelian randomization (MR) to explore the causal associations between SLE and AILDs.

Methods: A two-sample MR analysis was performed using summary-level statistics sourced from genome-wide association study (GWAS) datasets.

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Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by high blood glucose levels resulting from insulin resistance and impaired insulin secretion. Immune dysregulation-mediated chronic low-grade inflammation is a critical factor that poses a significant risk to the metabolic disorders of T2DM and its related complications. Exosomes, as small extracellular vesicles secreted by various cells, have emerged as essential regulators of intercellular communication and immune regulation.

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Background: Psoas abscess (PA) is an uncommon disease that has been increasingly reported in the recent years. We reviewed patients with PA and analyzed their clinical characteristics to improve our understanding of this rare disorder.

Methods: We retrospectively reviewed the clinical presentations, microbiology, and outcomes of patients with PA between 2011 and 2022 at the Zhejiang Provincial People's Hospital in China.

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  • Autoimmune hepatitis (AIH) is a common liver disease, but there are no effective noninvasive tests for assessing liver fibrosis in these patients, prompting the need for a new predictive model.
  • The study analyzed data from 374 AIH patients and developed a prediction model using logistic regression, which was validated on additional patient data to ensure its reliability.
  • Key factors like age, platelet count, and A/G ratio were found to be significant indicators of liver fibrosis, and the new model outperformed existing methods (APRI and FIB-4) in accuracy.
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Background: Obesity and related diseases have become one of the leading causes of death worldwide, which has been linked to biopsychosocial effects such as type 2 diabetes, cardiovascular disease, various cancers, depression, and weight stigma. Episodic future thinking (EFT) has been found to support the development of changes in health behaviors. However, the effectiveness of EFT in enhancing weight loss behavior and health outcomes is not well supported.

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With the increasing use of technology in nursing, how nurses perform practice care has changed, inevitably leading to ethical concerns that differ from original ethical norms in nursing. Studies have focused on ethical issues in health informatics from clinicians' or patients' perspectives, while nurses' perspective is needed. This paper conducts a theoretical study on ethical predicaments that arise in nursing informatics from nurses' perspectives.

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Background: Concurrent non-alcoholic fatty liver disease (NAFLD) is common in patients with chronic HBV infection. But the impact of fatty liver on the histologic progression of HBV infection remains controversial.

Methods: Consecutive HBV-infected patients who underwent liver biopsy between 2016 and 2021 were included.

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Article Synopsis
  • Hepatitis E virus infection is primarily known for causing liver-related symptoms but can also lead to serious conditions like immune-mediated thrombotic thrombocytopenic purpura (TTP), as illustrated in a unique case study.
  • A 53-year-old male patient presented with fever, low platelet count (thrombocytopenia), and liver dysfunction, ultimately diagnosed with acute hepatitis E, which triggered TTP.
  • Following specific treatments, including plasmapheresis and glucocorticoids, the patient showed significant improvement, highlighting the importance of screening for hepatitis E in patients with liver issues and low platelet counts.
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The purpose of this study is to investigate the efficacy of bilateral upper-limb training (BULT) in helping people with upper-limb impairments due to stroke or brain illness regain their previous level of function. Patients recuperating from a stroke or cerebral disease were given the option of undergoing BULT or conventional training to enhance their upper-limb function. Participants were randomly allocated to one of the several different fitness programs.

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Purpose: Time-consuming culture methods and wet-mount microscopy (WMM) with low sensitivity have difficulties in diagnosing Vulvovaginal candidiasis (VVC). Rapid and highly sensitive polymerase chain reaction coupled with quantum dot fluorescence analysis (PCR-QDFA) for the diagnosis of VVC has not been reported to date. This study was the first to evaluate the performance of PCR-QDFA for diagnosis of strains in the leukorrhea samples from patients with suspected VVC.

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Thyroid cancer is the most common endocrine cancer, and its prevalence has been increasing for decades. Approx. 95% of differentiated thyroid carcinomas are treated using iodine (I), a radionuclide with a half-life of 8 days, to achieve optimal thyroid residual ablation following thyroidectomy.

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Introduction: Current guidelines discourage the use of direct-acting antiviral (DAA) containing protease-inhibitor (PI) in advanced HCV cirrhosis. We aimed to compare the real-world tolerability of PI vs. non-PI DAA regimens in this population.

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