Publications by authors named "Hongyang Gong"

Objective: Infertility is associated with obesity. The Body Roundness Index (BRI) is a body measurement index related to obesity that more accurately assesses body and visceral fat levels. However, the relationship between BRI and infertility remains unclear.

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Article Synopsis
  • Extracellular vesicles (EVs) are membrane-bound structures released by brain cells, playing an increasingly recognized role in neurodegenerative diseases.
  • Research has shifted from basic biology of EVs to their clinical applications, particularly in identifying biomarkers and therapeutic targets for these diseases.
  • The review discusses the characteristics, functions, and biological mechanisms of different types of brain-derived EVs, along with potential therapeutic strategies and challenges in using EVs for drug delivery.
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Background: The Planetary Health Diet (PHD) is a novel dietary pattern proposed by the EAT-Lancet Commission in 2019, yet a limited study has investigated the anti-aging effects of PHD to date.

Objectives: This study aimed to explore the association between adherence to PHD, as quantified by the Planetary Health Diet Index (PHDI), and biological aging in American populations.

Methods: Data were obtained from the National Health and Nutrition Examination Survey (NHANES) for 1999-2018.

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A correlation between omega-3 polyunsaturated fatty acids (omega-3 PUFAs) and osteoarthritis (OA) incidence has been established, but research on the long-term outlook of OA patients remains limited. This study investigates the association between omega-3 PUFA intake and the risk of all-cause and cardiovascular (CV) mortality in the U.S.

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Background: Numerous studies have indicated a potential correlation between COPD, lipid metabolism, and dietary inflammation. However, the exact mechanisms by which dietary inflammation regulates the pathological processes of COPD related to lipid metabolism remain unclear. NHHR is a novel composite index of atherosclerotic lipid profiles, while the Dietary Inflammatory Index (DII) measures diet-induced inflammation.

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Background: Given the global shifts in environmental conditions and dietary habits, understanding the potential impact of dietary factors and body mass index (BMI) on respiratory diseases, including asthma, is paramount. Investigating these relationships can contribute to the formulation of more effective prevention strategies. The Planetary Health Diet Index (PHDI), a dietary scoring system that balances human health with environmental sustainability, underscores the importance of increasing the consumption of plant-based foods while reducing the intake of red meat, sugar, and highly processed foods.

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Limited research has explored the relationship between overactive bladder (OAB) and cardiovascular health (CVH). We aim to examine the correlation between OAB and CVH in American adults, utilizing the Life's Essential 8 (LE8). We included 70,190 individuals from the National Health and Nutrition Examination Survey spanning from 2005 to 2018.

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Exposure to bisphenol S (BPS) is known to adversely affect neuronal development. As pivotal components of neuronal polarization, axons and dendrites are indispensable structures within neurons, crucial for the maintenance of nervous system function. Here, we investigated the impact of BPS exposure on axonal and dendritic development both in vivo and in vitro.

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Tris (1,3-dichloro-2-propyl) phosphate (TDCPP), a halogen-containing phosphorus flame retardant, is widely used and has been shown to possess health risks to humans. The sustained release of artificial nanomaterials into the environment increases the toxicological risks of their coexisting pollutants. Nanomaterials may seriously change the environmental behavior and fate of pollutants.

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Article Synopsis
  • The rise in the use of titanium dioxide nanoparticles (TiO NPs) has raised concerns about their potential environmental contamination and health risks to humans, leading to increased research on their effects.
  • Exposure to TiO NPs has been linked to various neurotoxic effects, such as oxidative stress, neuroinflammation, and impaired neuronal function, which may result in behavioral disorders or contribute to neurodevelopmental and neurodegenerative diseases.
  • Current research has not fully explored the neurotoxic mechanisms and the varying effects of different TiO NPs under diverse exposure conditions, highlighting the need for more comprehensive studies to assess the risks associated with these nanoparticles.
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Titanium dioxide nanoparticles (TiO NPs) are widely used in several consumer products. However, because of their neurotoxic nature, exposure to TiO NPs could impair locomotor behavior. Whether the impairment in locomotor behavior caused by TiO NPs exposure is sustained and the effects is gender-specific has remained elusive, warranting further studies to elucidate the underlying mechanisms.

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Developing a straightforward and effective hydrophobic modification for metal-organic frameworks (MOFs) under mild conditions is meaningful for MOF applications. Here, a post-synthetic modification approach assisted with metal hydroxyl groups at room temperature is reported to induce hydrophobicity in the hydrophilic UiO-66. The bonding between Zr-OH in UiO-66 and n-tetradecylphosphonic acid (TDPA) is the vital force for the modifier TDPA.

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Background: In daily life and work, there are more and more patients with trauma to the hand, which often results in skin and soft tissue defects. Although there are many repair methods, the function and appearance of the fingers will be adversely affected if the repair is inadequate.

Case Summary: In the present report we describe an 18-year-old male patient whose right hand was mangled by a machine.

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