Intraosseous regional prophylactic antibiotics decrease the risk of infection in total knee arthroplasty compared with intravenous antibiotics: a systematic review and meta-analysis.

Purpose: Surgical site infection (SSI) is a rare and serious complication of total knee arthroplasty (TKA), which causes a poor prognosis for patients. The purpose of this study was to explore the effect of intraosseous (IO) antibiotics in preventing infection and complications after TKA compared with intravenous (IV) antibiotics and to provide a certain theoretical basis for clinical treatment.

Methods: The review process was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.

Clinical and Airway Inflammation Features of COPD Patients with Positive Bronchodilator Test.

Objective: To explore the difference in clinical characteristics and airway inflammation in chronic obstructive pulmonary disease (COPD) patients on the positive bronchodilator tests.

Study Design: Descriptive study.

Place And Duration Of Study: Affiliated Hospital of Shaoxing University, Shaoxing, China, from January to December 2017.