Changes of forests with embankment dams along the Laizhou bay.

Background: Embankment dams were built south of the Laizhou bay in China for controlling storm surge disasters, but they are not enough to replace coastal forests in protecting the land. This study was designed to evaluate the effects of embankment dams on natural forests dominated by and test whether the dam-shrub system is a preferable updated defense.

Methods: Coastal forests on two typical flats, one before and one behind embankment dams, were investigated using quadrats and lines.

The Yellow River is the key corridor for to disperse from Asia inlands to east seashores.

Plants of the L. genus (Tamaricaceae) mainly occur in arid inlands of Asia, but a few species occur in the coastal areas of China, and the Yellow River may account for this. This study was conducted to elucidate whether and how the Yellow River affects the pattern and development of the genus, involving two critical species of Nakai and Lour.

Dual-responsive electrochemical immunosensor for CYFRA21-1 detection based on Au/Co Co-loaded 3D ordered macroporous carbon interconnected framework.

Cytokeratin 19 fragment antigen 21-1 (CYFRA21-1) is a protein fragment released into the bloodstream during the death of lung epithelial cells, serving as a predictive biomarker in diagnosing non-small cell lung cancer (NSCLC) and need to be accurately detected. Herein, a dual-responsive label-free electrochemical immunosensor was developed based on a three-dimensional ordered interconnecting macroporous carbon skeleton material modified with gold-cobalt nanoparticles (Au/Co NPs-3D MCF) to detect cytokeratin-19 fragment (CYFRA21-1). The three-dimensional ordered interconnect macroporous structure, by providing a high specific surface area and an electrochemically active area, not only enhances the electron transport channel and reduces mass transfer resistance, but also offers a confined region that elevates the collision frequency with the active site.

Au NPs modified Ni-B nanosheets/graphene oxide three-dimensional network as label-free electrochemical immunosensor for the detection of diethylstilbestrol.

Three-dimensional (3D) network provide a promising platform for construction of high sensitive electrochemical immunosensor due to the benefits of high specific surface area and electron mobility. Herein, a sensitive label-free electrochemical immunosensor based on Au nanoparticles modified Ni-B nanosheets/graphene matrix was constructed to detect diethylstilbestrol (DES). The 3D network not only could increase the electron transport rate and surface area, but also could provide confinement area, which is conducive to increases the collision frequency with the active site.

Ultra-Sensitive Simultaneous Detection of Dopamine and Acetaminophen over Hollow Porous AuAg Alloy Nanospheres.

Hollow porous AuAg nanospheres (AuAg HPNSs) were obtained through a simple solvothermal synthesis, complemented by a dealloying strategy. The hollow interior, open pore voids, and integral interconnected skeleton shell in AuAg HPNSs are beneficial for providing sufficient electrolyte diffusion and contacts, abundant active sites, and efficient electron transport. This specific structure and the favorable alloy synergism contribute to the superior electrocatalytic activity toward dopamine (DA) and acetaminophen (AC).

[Dynamic changes of diaphragm and limb skeletal muscle in patients with sepsis assessed by bedside ultrasound and their correlation with blood urea/creatinine ratio].

Objective: To investigate the dynamic changes of diaphragm and limb skeletal muscle in patients with sepsis by bedside ultrasound and their correlation with the ratio of blood urea/creatinine ratio (UCR) in 7 days after intensive care unit (ICU) admission.

Methods: A prospective observational study was conducted. A total of 55 patients with sepsis admitted to ICU of General Hospital of Ningxia Medical University from June 2022 to February 2023 were selected as the research objects.

Self-powered photochemical cathode aptamer sensor based on ZnInS photoanode and CuO@Ag@AgPO photocathode for the sensitive detection of Hg.

A self-powered photoelectrochemical (PEC) aptamer sensor based on ZnInS as the photoanode and CuO@Ag@AgPO as the sensing cathode is designed for the detection of Hg. An indium tin oxide (ITO) electrode modified with ZnInS was used instead of a platinum (Pt) counter electrode to provide an obviously stable photocurrent signal. The suitable band gap width of ZnInS can generate photogenerated electrons well.

[The dynamic monitoring of gastric residual volume by ultrasound was used to guide the early nutritional treatment of patients with severe mechanical ventilation to gradually achieve the standard].

Objective: To explore the application value of dynamic monitoring of gastric residual volume (GRV) in achieving different target energy in severe mechanical ventilation patients.

Methods: A prospective randomized controlled study was conducted. Forty-two patients with mechanical ventilation admitted to the department of critical care medicine of General Hospital of Ningxia Medical University from July to December 2022 were enrolled.

Hydrogen Attenuates Thyroid Hormone-Induced Cardiac Hypertrophy in Rats by regulating angiotensin II type 1 receptor and NADPH oxidase 2 mediated oxidative stress.

Cardiac hypertrophy occurs as a result of high levels of thyroid hormone, which may contribute to heart failure and is closely related to oxidative stress. Hydrogen is a good antioxidant. In this study, we found that intragastric levothyroxine administration for two weeks caused obvious cardiac hypertrophy without reduced systolic function.

Environmental changes in Yellow River Delta with terrace construction and agricultural cropping.

Background: Crude flats in delta areas are often saline-alkaline and unsuitable for agricultural cropping. In the 1990s, people residing in the Yellow River delta constructed terraces on the flats for agricultural development. Herein, we investigated environmental changes resulting from this agricultural development and evaluated whether the current land use is effective and sustainable.

Hydrogen gas inhalation ameliorates cardiac remodelling and fibrosis by regulating NLRP3 inflammasome in myocardial infarction rats.

It is noteworthy that prolonged cardiac structural changes and excessive fibrosis caused by myocardial infarction (MI) seriously interfere with the treatment of heart failure in clinical practice. Currently, there are no effective and practical means of either prevention or treatment. Thus, novel therapeutic approaches are critical for the long-term quality of life of individuals with myocardial ischaemia.

Hydrogen Attenuates Myocardial Injury in Rats by Regulating Oxidative Stress and NLRP3 Inflammasome Mediated Pyroptosis.

Hydrogen (H) is an antioxidant with anti-inflammatory and apoptosis functions.This study aimed to estimate the effects of H on acute myocardial infarction (AMI) in rats and its association with the inhibition of oxidative stress and cardiomyocyte pyroptosis. Sixty-four rats were randomly divided into three groups (Sham, AMI, and H).

MicroRNA-181b Serves as a Circulating Biomarker and Regulates Inflammation in Heart Failure.

Heart failure (HF) is the typical terminal stage of cardiac diseases involving inflammatory states. The function of microRNAs (miRNAs) in the progress of HF remains poorly understood. In this study, real-time PCR results showed a decreased expression of miRNA-181b (miR-181b) in HF patients compared with healthy individuals.

Porous PtAg nanoshells/reduced graphene oxide based biosensors for low-potential detection of NADH.

A superior NADH sensing platform was constructed based on porous PtAg nanoshells supported on reduced graphene oxide (PtAg/rGO) in the absence of any enzymes and redox mediators. The PtAg/rGO composite was prepared via one-step reduction combined with galvanic replacement reaction. The as-made PtAg/rGO assembles multiple structural advantages of coherent conductive matrix, rich electroactive sites, and high specific surface area, accompanied by the unique alloying effect.

Nanoporous platinum-copper flowers for non-enzymatic sensitive detection of hydrogen peroxide and glucose at near-neutral pH values.

Multimodal nanoporous PtCu flowers (np-PtCu) were prepared via a two-step dealloying strategy under mild conditions. The np-PtCu alloy possesses an interconnected flower-like network skeleton with multiscale pore distribution. This material was placed on a glassy carbon electrode where it shows outstanding detection performance towards hydrogen peroxide and glucose in near-neutral pH solutions.

Inhalation of Hydrogen Attenuates Progression of Chronic Heart Failure via Suppression of Oxidative Stress and P53 Related to Apoptosis Pathway in Rats.

Continuous damage from oxidative stress and apoptosis are the important mechanisms that facilitate chronic heart failure (CHF). Molecular hydrogen (H) has potentiality in the aspects of anti-oxidation. The objectives of this study were to investigate the possible mechanism of H inhalation in delaying the progress of CHF.

An ultrasensitive biosensor for superoxide anion based on hollow porous PtAg nanospheres.

The accurate detection of the superoxide anion (O) has vital academic and medical diagnostic significance due to its important dual roles in biological functioning. In this work, hollow porous PtAg nanospheres (PtAg HPNSs) were fabricated by a facile hydrothermal method followed by a dealloying procedure. The as-made PtAg nanospheres possessed hollow interiors and porous shells composed of interconnected ligaments and pores with the typical size around 4 nm.

Successive Interfacial Reaction-Directed Synthesis of CeO@Au@CeO-MnO Environmental Catalyst with Sandwich Hollow Structure.

Noble metal nanoparticle-based catalysts are widely used for the removal of hazardous materials. During the catalytic reactions, it is of particular importance for developing novel strategies to avoid the leaching or sintering of noble metal nanoparticles. Here, the 4-nitrophenol (4-NP) and CO, typical hazardous chemicals in industrial water and exhaust gases from vehicles, are studied for their removal using CeO@Au@CeO-MnO catalyst.

Conservation choice on the rare endangered plants .

The coastal herbs have been domesticated as traditional medicines for many centuries. The domestication may have caused changes or declines of cultivated (CGL) relative to wild (WGL). By comparing fruit properties of CGL and WGL, we tested the hypothesis that domesticated have suffered major declines, and human cultivation cannot be sufficient to conserve this species.

Hierarchical nanoporous platinum-copper alloy nanoflowers as highly active catalysts for the hydrolytic dehydrogenation of ammonia borane.

Hierarchical nanoporous platinum-copper (hnp-PtCu) alloy nanoflowers with bimodal pore/ligament size are easily fabricated by selectively dissolving Al atoms and part of Cu atoms from PtCuAl ternary alloy. The dealloyed samples consist of cross-linking porous nanoflowers with interconnected network skeleton and hollow channels penetrated. Hnp-PtCu alloy nanoflowers with different compositions exhibit dramatically enhanced catalytic activities toward the hydrolysis of ammonia borane (AB) compared with their monometallic components.

Hydrogen Gas Attenuates Myocardial Ischemia Reperfusion Injury Independent of Postconditioning in Rats by Attenuating Endoplasmic Reticulum Stress-Induced Autophagy.

Background/aims: To study the effect of inhaling hydrogen gas on myocardial ischemic/reperfusion(I/R) injury in rats.

Methods: Seventy male Wistar albino rats were divided into five groups at random as the sham group (Sham). The I/R group (I/R), The ischemic postconditioning group (IPo), The I/R plus hydrogen group (IH2) and the ischemic postconditioning plus hydrogen group (IPoH2).

Natural persistence of the coastal plant Glehnia littoralis along temperate sandy coasts.

We studied germination behaviors and persistence mechanism of wild Glehnia littoralis, a typical coastal species at temperate sandy coasts of the North Pacific Ocean, and tested the hypothesis that the coastal plants may have evolved special seeds adapting to the coasts, by which they recruit and persist easily, occupying the coasts as ideal habitats. In the Shandong Peninsula, China, we investigated temperature and moisture conditions of coast sand in relation to germination and evaluated effects of sand burial, seawater immersion and sowing time on germination. When germination began, daily dawn temperatures of sand were about 10 °C and daily noon temperatures were about 25 °C; the temperatures were not different in the sand <8 cm deep.

Hydrogen-Rich Saline Attenuates Cardiac and Hepatic Injury in Doxorubicin Rat Model by Inhibiting Inflammation and Apoptosis.

Doxorubicin (DOX) remains the most effective anticancer agent which is widely used in several adult and pediatric cancers, but its application is limited for its cardiotoxicity and hepatotoxicity. Hydrogen, as a selective antioxidant, is a promising potential therapeutic option for many diseases. In this study, we found that intraperitoneal injection of hydrogen-rich saline (H saline) ameliorated the mortality, cardiac dysfunction, and histopathological changes caused by DOX in rats.

Nanoporous PdCu alloy as an excellent electrochemical sensor for HO and glucose detection.

Nanoporous (NP) PdCu alloy is easily fabricated by dealloying PdCuAl ternary alloy in dilute sulfuric acid. Selectively dissolving Al from PdCuAl alloy generates the three-dimensional uniform nanosponge architecture with narrow ligament size distribution. Benefitting from the unique nanoporous architecture and the alloying effect, the as-made NP-PdCu exhibits outstanding sensing performance towards the detection of hydrogen peroxide (HO) and glucose.