ALDH5A1 acts as a tumour promoter and has a prognostic impact in papillary thyroid carcinoma.

Thyroid cancer is the most common endocrine carcinoma, with papillary thyroid carcinoma (PTC) accounting for 80%-90% of thyroid cancers. Accumulating studies reported that mitochondria plays an important role in the regulation of cell proliferation. ALDH5A1, may function as an oncogene or tumour suppressor in various human cancers, and the role of ALDH5A1 in PTC is still unclear.

Characteristics and removal of microplastics in rural domestic wastewater treatment facilities of China.

The environment of the countryside is different from that of the city. Studying the abundance, characteristics, and removal of microplastics (MPs) in rural domestic wastewater treatment facilities (RD-WWTFs) is of great significance for understanding the impacts of human activities on the environment of the countryside. Therefore, we studied five such facilities in the Hangzhou region of China.

[Nucleotide sequence analysis for a new HLA-B allele HLA-B*13:01:06*].

Objective: To confirm a new allele HLA-B*13:01:06 and analyze its nucleotide sequence.

Methods: Genomic DNA was extracted using a Qiagen DNA extraction kit. Nucleotide sequences of HLA-A, HLA-B, HLA-C and HLA-DRB1 were analyzed by polymerase chain reaction-sequence based typing (PCR-SBT).

[Full sequence analysis for a null allele of MICA gene (MICA*063N)].

Objective: To analyze the full nucleotide sequence of a null allele of major histocompatibility complex class I chain-related gene (MICA).

Methods: A sequence-based typing method was used to determine the nucleotide sequence of the MICA gene. Potential alleles were identified with a computer program.