Novel heterozygous variant of causes pathogenic variation in CONDSIAS.

Adprhl2 (OMIM: 610624) mutation associated stress-induced childhood-onset neurodegeneration with variable ataxia and seizures (CONDSIAS, OMIM: 618170) is a sporadic neurodegenerative disease with poor prognosis. encodes ADP-ribosylhydrolase 3 (ARH3), which participates in ADP-ribosylation to remove poly-ADP ribose (PAR). We found a new compound heterozygous mutation in the gene c.

Effect of automatic emotional processing on response inhibition among heroin abstainers.

Previous studies have explored effects of the conscious processing of emotional information on the interaction between emotion and executive control. However, the conscious processing of emotional information introduces "defensive responses," which might limit the emotional effect. To avoid the limitations, this study aimed to explore the effect of automatic emotional processing on response inhibition among heroin abstainers.

Updating Emotional Stimuli in Heroin Abstainers' Working Memory: An Event-Related Potential Investigation.

Background: It is well-documented that heroin users demonstrate aberrant emotion-processing abilities. However, the mechanism by which heroin users process emotional information after it has captured their attention and entered their working memory is unclear.

Objectives: A modified emotional 2-back task was used to examine whether heroin abstainers demonstrate specific bias patterns in updating emotional stimuli in their working memory.