FOXL2 regulates RhoA expression to change actin cytoskeleton rearrangement in granulosa cells of chicken pre-ovulatory follicles†.

Forkhead box L2 (FOXL2) is an indispensable key regulator of female follicular development, and it plays important roles in the morphogenesis, proliferation, and differentiation of follicle granulosa cells, such as establishing normal estradiol signaling and regulating steroid hormone synthesis. Nevertheless, the effects of FOXL2 on granulosa cell morphology and the underlying mechanism remain unknown. Using FOXL2 ChIP-seq analysis, we found that FOXL2 target genes were significantly enriched in the actin cytoskeleton-related pathways.

Efficient electrocatalytic reduction of nitrate to ammonia over fibrous SmCoO under ambient conditions.

We report SmCoO nanofibers as an efficient catalyst for nitrate reduction to ammonia. This catalyst achieves a large NH yield of 14.4 mg h mg.

Durable Electrocatalytic Reduction of Nitrate to Ammonia over Defective Pseudobrookite Fe TiO Nanofibers with Abundant Oxygen Vacancies.

We propose the pseudobrookite Fe TiO nanofiber with abundant oxygen vacancies as a new electrocatalyst to ambiently reduce nitrate to ammonia. Such catalyst achieves a large NH yield of 0.73 mmol h  mg and a high Faradaic Efficiency (FE) of 87.

Heterogenous Cu@ZrO nanofibers enable efficient electrocatalytic nitrate reduction to ammonia under ambient conditions.

In this study, we construct a Cu@ZrO heterogenous structure as a new catalyst that achieves a large NH yield of 15.4 mg h mg. and a high faradaic efficiency of 67.

FOXL2 regulates the expression of the Col4a1 collagen gene in chicken granulosa cells.

Forkhead box L2 (FOXL2), one member in the superfamily of forkhead transcription factors, is a core transcription factor specifically expressed in ovarian granulosa cells and is essential for the development of follicles. FOXL2 has been shown to regulate the transcription of genes encoding enzymes that synthesize steroid hormones and estrogen receptors and regulate the expression of collagen genes in granulosa cells. This study explored the effect of FOXL2 on collagen gene expression in granulosa cells by overexpressing Foxl2 in pregranulosa cells, prehierarchical follicles and preovulation follicle granulosa cells.