Bioinformatics and Machine Learning-Based Identification of Critical Biomarkers and Immune Infiltration in Venous Thromboembolism.

This study aims to use bioinformatics and machine learning algorithms to screen and analyze the key genes involved in venous thromboembolism (VTE) and explore the relationship between these biomarkers and immune cell infiltration. The gene expression profile with the identifier GSE19151 was downloaded from the GEO database. Differential expression analysis using the limma package was conducted to identify genes that were differentially expressed between VTE and normal samples.

TYROBP as a molecular target in cholangiocarcinoma, renal cancer and abdominal aortic aneurysm.

Cholangiocarcinoma occurs when there is a malignant tumor in the bile duct system. Renal cancer originates from renal tubular epithelial cells. Abdominal aortic aneurysm (AAA) is a permanently localized dilation caused by a lesion or injury to abdominal aortic wall.

Higher expression of PLEK and LY86 as the potential biomarker of carotid atherosclerosis.

Carotid atherosclerosis (AS) occurs in atherosclerotic lesions of the carotid artery, which can lead to transient ischemic attack and stroke in severe cases. However, the relationship between pleckstrin (PLEK) and lymphocyte antigen 86 (LY86) and carotid AS remains unclear. The carotid AS datasets GSE43292 and GSE125771 were downloaded from the gene expression omnibus database.

A case study on thrombolytic treatment of acute aortic saddle embolism using bilateral femoral arterial puncture catheter.

Although peripheral arterial embolism is a common vascular disease, abdominal aortic saddle embolism (ASE) is rare. However, ASE is considered to be quite severe. A rapid and accurate diagnosis followed by timely and appropriate medical intervention is the key to minimize the risk of severe complications and reduce the risk of mortality.

Percutaneous Endovenous Intervention Plus Anticoagulation versus Anticoagulation Alone for Treating Patients with Proximal Deep Vein Thrombosis: A Meta-analysis and Systematic Review.

Background: Combination treatment with percutaneous endovenous intervention (PEVI) and anticoagulation has been proposed for treating lower-extremity proximal deep vein thrombosis (DVT). We performed a systematic review and meta-analysis of randomized controlled trials (RCTs) to assess the effect of PEVI plus anticoagulation versus anticoagulation alone in patients with lower-extremity proximal DVT.

Methods: We systematically searched PubMed, Embase, and the Cochrane Library from inception to May 2016.

Thoraco-abdominal aorta revascularization through a retroperitoneal approach.

Objective: To investigate the application of the retroperitoneal approach in aortic surgery.

Methods: We collected and analyzed data of 7 patients in Macau who presented with aortic diseases from 2007 to 2008 and were treated with aorta repair through retroperitoneal approach. Demographic features as well as intraoperative and postoperative data were analyzed.

Hybrid endovascular aorta repair with simultaneous supra-aortic branch or iliac branch revascularization.

Objective: To describe a hybrid endovascular procedure for aorta repair with different kinds of bypass followed by concomitant placement of stent graft in the aorta.

Methods: From June 2007 to May 2008, 5 consecutive patients who presented with aortic aneurysm or dissection were treated with a new hybrid aorta repair technique. Complete surgical rerouting of supra-aortic vessels was simultaneously created by endovascular repair of aortic arch aneurysm with stent graft.