Increased METTL3 expression and mA RNA methylation may contribute to the development of dry eye in primary Sjögren's syndrome.

Background: Primary Sjögren's syndrome (pSS) is a chronic autoimmune disorder defined by xerostomia and keratoconjunctivitis sicca, and its etiology remains unknown. N6-methyladenosine (mA) is the predominant posttranscriptional modification in eukaryotic mRNAs and is dynamically regulated by mA regulators. Dysregulation of mA modification is closely associated with several autoimmune disorders, but the role of mA modification in pSS remains unknown.

Effect of interaction between Pd and Fe in modified red mud on catalytic decomposition of toluene.

As an industrial solid waste produced by alumina industry, red mud was modified as support of Pd catalysts for toluene catalytic oxidation in this paper. The xPd/MRM catalysts had high activity for toluene catalytic oxidation, and the 0.3Pd/MRM catalyst showed the best catalytic performance (T = 175 °C and T = 200 °C).