Publications by authors named "Hongpeng Du"
Introduction: Long non-coding RNA (LncRNA) plays a critical role in cerebral ischemia-reperfusion (CI/R) injury. The purpose of the current research was to investigate the regulatory role of the LncRNA human leukocyte antigen complex group 11 (HCG11) in CI/R injury and explore its potential mechanism.
Material And Methods: The rat middle cerebral artery occlusion (MCAO) model was established to simulate CI/R injury in vivo.
Article Synopsis
- * A variety of port sizes were created using common surgical materials (gloves and syringes), allowing for successful endoscopic procedures in seven patients without complications.
- * The findings suggest that this glove-syringe system is a practical alternative to expensive commercial ports, especially beneficial in rural settings where resources may be limited.
Objective: At present, there is no consensus regarding the standard treatment for glioblastoma (GBM) in elderly patients with impaired Karnofsky performance status (KPS) scores. This study aimed to determine the effects of temozolomide (TMZ) versus best supportive care (BSC) in this population.
Materials And Methods: We conducted a retrospective observational study of patients aged ≥65 years with histologically confirmed GBM and KPS scores ≤70 who were treated at our institution between January 2006 and July 2014.
Pituitary tumors are the most common type of cancer within the central nervous system. In the present study, the expression levels of mucin 1 (Muc1) were examined in invasive and non‑invasive pituitary tumor samples, and the results of immunohistochemical staining and Western blot analysis demonstrated marked positive expression of Muc1. In addition, Muc1 + polyinosinic:polycytidylic acid (poly I:C) was found to stimulate the expression levels of the surface molecules cluster of differentiation (CD)40, CD83 and CD80, and HLA‑DRm and decreased the expression of CD14 in the dendritic cells, determined using fluorescence‑activated cell sorting.
View Article and Find Full Text PDF[CLINICAL RESEARCH AND DISCUSSION OF MODIFIED CRANIOPLASTY].
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
July 2015
Objective: To study and design a modified cranioplasty, and to explore the effectiveness so as to reduce the incidence rate of operative complications.
Methods: A total of 68 patients with craniocerebral trauma or hypertensive cerebral hemorrhage between August 2012 and March 2014 were selected and randomly divided into 2 groups. The standard decompress craniectomy and under-temporal cranioplasty were performed in 32 cases (group A), and several small bone chips were placed under-tempus during decompress craniectomy and then the shape of temporal muscle was designed and the temporal muscle was reconstructed at the attachment sites during cranioplasty in 36 cases (group B).