EDN1 and NTF3 in keloid pathogenesis: computational and experimental evidence as novel diagnostic biomarkers for fibrosis and inflammation.

Objective: To investigate the roles of oxidative stress-related differentially expressed genes (OSRDEGs) in keloid formation and explore their potential value in diagnosis and treatment.

Methods: Gene expression data from the GEO database, including GSE145725 and GSE44270 as training sets and GSE7890 as a validation set, were utilized. OSRDEGs were identified, followed by Weighted Gene Co-expression Network Analysis (WGCNA), GO/KEGG enrichment analysis, and Gene Set Enrichment Analysis (GSEA).

Cu/Co Bimetallic Carbon Catalyst as a Highly Efficient Promoter for Reactive Dyes Degradation with PMS.

The synergistic effect between bimetallic catalysts has been confirmed as an effective method for activating persulfate (PMS). Therefore, we immobilized copper-cobalt on chitosan to prepare bimetallic carbon catalysts for PMS activation and degradation of reactive dyes. Experimental results demonstrate that the CuCo-CTs/PMS catalytic degradation system exhibits excellent degradation performance toward various types of reactive dyes (e.

Knockdown of growth differentiation factor-15 inhibited nonsmall cell lung cancer through inactivating PTEN/PI3K/AKT signaling pathway.

Background: Non-small cell lung cancer (NSCLC) is characterized by high morbidity and mortality in the world. Growth and differentiation factor 15 (GDF15) has been proved to play an important role in regulating tumor progression. However, the influence of GDF15 on NSCLC remains unclear.

ER Stress-Related Genes EIF2AK3, HSPA5, and DDIT3 Polymorphisms are Associated With Risk of Lung Cancer.

This study aimed to evaluate the associations between endoplasmic reticulum (ER) stress-related genes PERK, GRP78, and CHOP polymorphisms and the risk of lung cancer. Six single-nucleotide polymorphisms (SNPs) of , , and were genotyped in 620 cases and 620 controls using a MassARRAY platform. The minor allele A of rs6750998 was a protective allele against the risk of lung cancer ( < 0.

Endoglucanase activity of cellulolytic bacteria from lake sediments and its application in hydrophyte degradation.

Hydrophytes are plants that grow in or on water. Their overgrowth adversely affects the ecosystem because of crowding out other aquatic organisms and polluting the environment with plant residue. In principle, cellulolytic bacteria can be used to degrade hydrophyte biomass.

Removal performance of antibiotics and antibiotic resistance genes in swine wastewater by integrated vertical-flow constructed wetlands with zeolite substrate.

Antibiotics and antibiotic resistance genes (ARGs) in swine wastewater have an irreversible impact on the surrounding water and soil ecosystems. Herein, integrated vertical-flow constructed wetlands (IVCWs) were constructed to assess the effects of zeolite and plants on the removal of sulfonamides (SMs), tetracyclines (TCs), and related ARGs (tetW, tetO, tetM, sul I, sul II, and sul III) from digested swine wastewater. The microorganism community structure was also investigated.