Targeting cytohesin-1 suppresses acute myeloid leukemia progression and overcomes resistance to ABT-199.

Adhesion molecules play essential roles in the homeostatic regulation and malignant transformation of hematopoietic cells. The dysregulated expression of adhesion molecules in leukemic cells accelerates disease progression and the development of drug resistance. Thus, targeting adhesion molecules represents an attractive anti-leukemic therapeutic strategy.

Neural Basis of Depression Related to a Dominant Right Hemisphere: A Resting-State fMRI Study.

Background: In the past, studies on the lateralization of the left and right hemispheres of the brain suggested that depression is dominated by the right hemisphere of the brain, but the neural basis of this theory remains unclear.

Method: Functional magnetic resonance imaging of the brain was performed in 22 depressive patients and 15 healthy controls. The differences in the mean values of the regional homogeneity (ReHo) of two groups were compared, and the low-frequency amplitudes of these differential brain regions were compared.

Emotion recognition from multichannel EEG signals using K-nearest neighbor classification.

Background: Many studies have been done on the emotion recognition based on multi-channel electroencephalogram (EEG) signals.

Objective: This paper explores the influence of the emotion recognition accuracy of EEG signals in different frequency bands and different number of channels.

Methods: We classified the emotional states in the valence and arousal dimensions using different combinations of EEG channels.