Publications by authors named "Hongna Fu"
Article Synopsis
- A study involving 20,034 patients with essential hypertension from the UK Biobank aimed to examine the link between leukocyte telomere length (LTL) and the risk of major adverse cardiovascular events (MACE) and mortality.
- The results indicated that patients with shorter LTL had a higher risk of experiencing MACE (adjusted HR 1.15) and increased mortality (adjusted HR 1.18) compared to those with longer LTL.
- The findings suggest that shorter LTL could serve as a potential predictor of health outcomes or could be targeted for therapeutic interventions in hypertensive patients.
Background: ST-segment elevation myocardial infarction (STEMI) persists to be prevalent in the elderly with a dismal prognosis. The capacity of endothelial progenitor cells (EPCs) is reduced with aging. Nevertheless, the influence of aging on the functionality of EPCs in STEMI is not fully understood.
View Article and Find Full Text PDFObjective: This study aimed to investigate the association between consumption of ultra-processed foods (UPFs) and leucocyte telomere length (LTL).
Methods: This cross-sectional study utilized data from the UK Biobank, including a total of 64,690 participants. LTL was measured using Q-PCR with natural logarithmic conversion and Z-score normalization.
Background: The relationships between sleep duration and aging-associated diseases are intricate. Leukocyte telomere length (LTL) is a biomarker of aging, while the association of sleep duration and LTL is unclear.
Methods: The 310,091 study participants from UK Biobank were enrolled in this cross-sectional study.
Based on the phase separation phenomenon of acetonitrile-water system at subzero temperature, a subzero-temperature liquid-liquid extraction coupled with ultra-performance liquid chromatography tandem quadrupole mass spectrometry : UPLC-MS-MS) method was developed for the simultaneous determination of 12 bioactive components in Gegen-Qinlian decoction. After optimization, the extraction conditions were set as follows: 3.0 mL of aqueous sample solution (pH 5.
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