Identification and Genomic Characterization of Two Novel Hepatoviruses in Shrews from Yunnan Province, China.

Hepatitis A virus (HAV), a member of the genus ( HepV), remains a significant viral pathogen, frequently causing enterically transmitted hepatitis worldwide. In this study, we conducted an epidemiological survey of HepVs carried by small terrestrial mammals in the wild in Yunnan Province, China. Utilizing HepV-specific broad-spectrum RT-PCR, next-generation sequencing (NGS), and QNome nanopore sequencing (QNS) techniques, we identified and characterized two novel HepVs provisionally named EpMa-HAV and EpLe-HAV, discovered in the long-tailed mountain shrew () and long-tailed brown-toothed shrew (), respectively.

Clinical and Molecular Epidemiology of Hemorrhagic Fever with Renal Syndrome Caused by Orthohantaviruses in Xiangyun County, Dali Prefecture, Yunnan Province, China.

Hemorrhagic fever with renal syndrome (HFRS) is a zoonotic disease transmitted by several rodent species. We obtained clinical data of HFRS patients from the medical records of the People's Hospital of Xiangyun County in Dali Prefecture from July 2019 to August 2021. We collected epidemiological data of HFRS patients through interviews and investigated host animals using the night clip or night cage method.

A case of pulmonary tuberculosis patient complicated with hemorrhagic fever with renal syndrome and scrub typhus in Yunnan, China: a case report.

Background: Hemorrhagic fever with renal syndrome (HFRS) caused by Orthohantavirus (OHV) and scrub typhus (ST) caused by Orientia tsutsugamushi (OT) are two infectious diseases prevalent in southwest China. Rodents are the natural host and the main source of the two diseases. OT infection to humans is usually resulted from bite of an infective chigger mite on rodents, and OHV is transmitted through contact or inhalation of aerosols and secretions from infected rodent.

AtANN1 and AtANN2 are involved in phototropism of etiolated hypocotyls of by regulating auxin distribution.

Phototropism is an essential response in some plant organs and features several signalling molecules involved in either photo-sensing or post-sensing responses. Annexins are involved in regulating plant growth and its responses to various stimuli. Here, we provide novel data showing that two members of the Annexin family in , AtANN1 and AtANN2, may be involved in the phototropism of etiolated hypocotyls.

P2K1 Receptor, Heterotrimeric Gα Protein and CNGC2/4 Are Involved in Extracellular ATP-Promoted Ion Influx in the Pollen of .

As an apoplastic signal, extracellular ATP (eATP) is involved in plant growth and development. eATP promotes tobacco pollen germination (PG) and pollen tube growth (PTG) by stimulating Ca or K absorption. Nevertheless, the mechanisms underlying eATP-stimulated ion uptake and their role in PG and PTG are still unclear.

Polybrominated Diphenyl Ethers and Heavy Metals in a Regulated E-Waste Recycling Site, Eastern China: Implications for Risk Management.

Serious pollution of multiple chemicals in irregulated e-waste recycling sites (IR-sites) were extensively investigated. However, little is known about the pollution in regulated sites. This study investigated the occurrence of 21 polybrominated diphenyl ethers (PBDEs) and 10 metals in a regulated site, in Eastern China.

Methylsiloxane occurrence and distribution in free-range poultry eggs near a rural industrial park: Indicators of potential risks to birds.

The ecological harm from methylsiloxanes has drawn worldwide attention. This study investigated three cyclic (D-D) and four linear siloxanes (L-L) in the eggs of free-range poultry collected near a rural industrial park in China and found total concentrations in the range of 19.2-1204 (median, 268) ng/g dry weight.

Methyl siloxanes in soils from a large silicone-manufacturing site, China: concentrations, distributions and potential human exposure.

Methyl siloxanes are widely found in the environment, but little is known about the distributions of these chemicals in soils especially in areas where they are manufactured. We determined the concentrations of four cyclic (D-D) and 13 linear methyl siloxanes (L-L) in the soils from a siloxane-manufacturing site in China; the total concentrations of these 17 siloxanes (TSi) in the soils were 17.1-3,191 (median, 134) ng/g.

Concentrations, distribution and risk of polycyclic aromatic hydrocarbons in sediments from seven major river basins in China over the past 20 years.

Polycyclic aromatic hydrocarbons (PAHs) in river sediments in China have been extensively investigated. However, most previous studies only reported information about specific locations. As a result, the distribution and changes of these chemicals in sediments nationwide remain unknown.

Global distribution and trends of polybrominated diphenyl ethers in human blood and breast milk: A quantitative meta-analysis of studies published in the period 2000-2019.

Polybrominated diphenyl ethers (PBDEs) are a class of flame-retardants that are found throughout the human body. However, global trends and diversity of the concentrations in human body and the potential risks remain largely unresolved. Based on published data during 2000-2019, we conducted a systematic meta-analysis to understand the burden and risks of PBDEs in humans and their spatiotemporal variations.

Methyl siloxanes in road dust from a large silicone manufacturing site in China: implications of human exposure.

Methyl siloxanes are becoming increasingly prevalent in the environment because of their extensive use in various consumer products. Little is known about the distribution of these chemicals around factories or their presence in road dust. We conducted a survey of four cyclic (D-D) and 13 linear (L-L) siloxanes in road dusts around a manufacturing site and found a total siloxane concentration range of 47.

Concentration profile, spatial distributions and temporal trends of polybrominated diphenyl ethers in sediments across China: Implications for risk assessment.

Polybrominated diphenyl ethers (PBDEs) in sediments of China have been extensively investigated; however, most studies conducted to date have focused on specific locations, and the pollution and risk posed by these chemicals in sediments at the national scale remain unknown. Therefore, we analyzed the concentrations and risks of PBDEs in sediments in China and their spatiotemporal variations based on available literature. Overall, the sediments across China contain moderate to high levels of PBDEs, with BDE-209 being the dominant congener, followed by BDE-47 and BDE-99.

MicroRNAs as a novel class of diagnostic biomarkers in detection of hepatocellular carcinoma: a meta-analysis.

MicroRNAs (miRNAs) have been proposed as promising diagnostic biomarkers for many diseases, particularly in the field of cancer research. Numerous studies have explored the use of miRNAs in the detection of hepatocellular carcinoma (HCC), with some reporting inconsistent results. Thus, we conducted this meta-analysis to evaluate the potential diagnostic value of miRNAs in HCC.

Wear behavior of seven artificial resin teeth assessed with three-dimensional measurements.

Statement Of Problem: Artificial resin teeth are widely used for removable dental prostheses because of their excellent properties. An evaluation of their wear behavior is important for predicting good clinical performance.

Purpose: The purpose of the study was to examine the wear behavior of 7 different artificial resin teeth with 3-dimensional measurements.

Influence of repeated insertion-removal cycles on the force and magnetic flux leakage of magnetic attachments: an in vitro study.

Statement Of Problem: Magnetic attachments are widely used in overdentures and maxillofacial prostheses. Because the patient will routinely have to insert and remove a removable prosthesis, the retentive force and magnetic flux leakage of the magnetic attachments after repeated insertion and removal must be evaluated to assess their clinical performance.

Purpose: The purpose of this in vitro study was to investigate the retentive force and flux leakage of magnetic attachments after repeated insertion and removal.

[An analysis of measurement error in Orbscan topography system].

Objective: To discuss the measurement error and the influence factor of Orbscan Topography to provide more accurate data for clinical application.

Methods: Orbscan Topography System and A-scan ultrasonography were used to measure the corneal thickness and anterior chamber depths pre-operatively and post-operatively, including 200 cases (400 eyes) undergoing laser in situ keratomileusis (Lasik) and 50 cases (100 eyes) undergoing photorefractive keratectomy (PRK). The curvature of posterior corneal surface was measured by Orbscan topography before and after the operations, and the result of measurement was compared.