Sex-specific differences in the relationship between thyroid hormones and neurocognition in schizophrenia: A large-scale cross-sectional study.

Background: Sex differences in thyroid hormones, cognitive function, and psychiatric symptoms in schizophrenia remain underexplored. The study aimed to investigate the cross-sectional relationships between thyroid hormone levels, cognitive impairments, and clinical symptoms in people with chronic schizophrenia, with a focus on sex differences.

Methods: We included 1007 people with schizophrenia (602 males and 405 females), and 326 healthy controls (193 males and 133 females).

Safety and effectiveness of oral medium to high dose blonanserin in patients with schizophrenia: subgroup analysis from a prospective, multicenter, post-marketing surveillance study in mainland China.

Background: Blonanserin (BNS) had been undergoing post-market surveillance (PMS) since September 2018. Using the surveillance data, we did this analysis to assess the safety and effectiveness of different doses of BNS to explore a sufficient dose range of BNS in Chinese patients with schizophrenia (SZ).

Methods: A 12-week, prospective, observational, single-arm, multicenter, open-label PMS was conducted.

[Study on depressive disorder and related factors in surgical inpatients].

Objective: To investigate the prevalence and possible influencing factors of depressive disorder in surgical inpatients.

Methods: Two hundred and sixty-six surgical inpatients meeting the inclusion criteria were first screened with the self rating depression scale (SDS), and then the subjects screened positive and 20% of those screened negative were evaluated with Structured Clinical Interview for DSM-IV Axis I Disorders (SCID) as a gold standard for diagnosis of depressive disorder. Possible influencing factors were also analyzed by experienced psychiatrists.