Degree of disorder-regulated ion transport through amorphous monolayer carbon.

Nanopore technology, re-fueled by two-dimensional (2D) materials such as graphene and MoS, controls mass transport by allowing certain species while denying others at the nanoscale and has a wide application range in DNA sequencing, nano-power generation, and others. With their low transmembrane transport resistance and high permeability stemming from their ultrathin nature, crystalline 2D materials do not possess nanoscale holes naturally, thus requiring additional fabrication to create nanopores. Herein, we demonstrate that nanopores exist in amorphous monolayer carbon (AMC) grown at low temperatures.

Ultrasensitive Biochemical Sensing Platform Enabled by Directly Grown Graphene on Insulator.

To fabricate label-free and rapid-resulting semiconducting biosensor devices incorporating graphene, it is pertinent to directly grow uniform graphene films on technologically important dielectric and semiconducting substrates. However, it has long been intuitively believed that the nonideal disordered structures formed during direct growth, and the resulted inferior electrical properties will inevitably lead to deteriorated sensing performance. Here, graphene biosensor chips are constructed based on direct plasma-enhanced chemical vapor deposition (PECVD) grown graphene on a 4-inch silicon wafer with excellent film uniformity and high yield.

[Evaluation of Heavy Metal Content, Sources, and Potential Ecological Risks in Soils of Southern Hilly Areas].

In order to explore the characteristics of soil heavy metal pollution and ecological risk status in southern hilly areas, a hilly area of a southern province was selected as the research area, using soil samples collected at 60 points in 2017. The single factor pollution index (), Nemero comprehensive pollution index, and potential ecological risk index (RI) were used to evaluate the content characteristics and potential ecological risks of eight heavy metal elements (As, Cd, Cr, Cu, Hg, Ni, Pb, and Zn), and positive definite matrix factor analysis models (PMF) were used to analyze their sources of pollution. The results were as follows:① the content of eight heavy metal elements in the study area exceeded the standard, and the Nemeiro comprehensive pollution index showed that the proportions of light, moderate, and heavy pollution in the study area were 63%, 8%, and 2%, respectively.

Dielectric-Modulated Biosensing with Ultrahigh-Frequency-Operated Graphene Field-Effect Transistors.

Owing to their excellent electrical properties and chemical stability, graphene field-effect transistors (Gr-FET) are extensively studied for biosensing applications. However, hinging on surface interactions of charged biomolecules, the sensitivity of Gr-FET is hampered by ionic screening under physiological conditions with high salt concentrations up to frequencies as high as MHz. Here, an electrolyte-gated Gr-FET in reflectometry mode at ultrahigh frequencies (UHF, around 2 GHz), where the ionic screening is fully cancelled and the dielectric sensitivity of the device allows the Gr-FET to directly function in high-salt solutions, is configured.

Glutathione S-transferase mu-1, glutathione S-transferase theta-1 null genotypes, and oral cancer risk: A meta-analysis in the Chinese population.

Aim Of Study: Several studies have evaluated the correlation between glutathione S-transferase mu-1 (GSTM1), GST theta-1 (GSTT1) polymorphisms and oral cancer in Chinese people. However, the results are inconsistent. To assess the effects of GSTM1, GSTT1 null genotypes on the risk for development of oral cancer in the Chinese population, a meta-analysis was performed.

[Relationship between dental caries and salivary proteome by electrospray ionization ion-trap tandem mass spectrometry in children aged 6 to 8 years].

Objective: To explore the relationship between salivary proteome and dental caries and to promote the biomarker studies of dental caries susceptibility by comparing the salivary proteome of caries-active children and caries-free children with electrospray ionization ion-trap tandem mass spectrometry (ESI-MS/MS).

Methods: Ten caries-active children and ten caries-free children were sampled. The salivary proteome of the two groups was studied, and the differential protein between the two groups was analyzed by ESI-MS/MS after sodium dodecyl sulfate polyacrylamide gel electrophoresis, filter-aided sample preparation, and liquid chromatography.

[RANKL and OPG expression in bone marrow-derived mesenchymal stem cells of ovariectomied promotes osteoclast development and enhances its function].

Objective: To investigate the expression of receptor activator of nuclear factor-kappa B lig (RANKL), osteoprotegerin (OPG) in bone marrow mesenchymal stem cells (BMSCs) and its impact on osteoclast formation and function in the ovariectomied mice.

Methods: An animal model of osteoporosis was established by ovariectomy (OVX bilateral ovarian resection) in 8-week-old healthy female mice. The sham group was the 8-week-old healthy female mice with bilateral resection.