Association between apolipoprotein E ε4 status and the risk of Alzheimer's disease: a meta-analysis.

Background: The apolipoprotein E ε4 (APOE ε4) status has a controversial role in predicting Alzheimer's disease (AD) factors. This meta-analysis assessed AD event risk in patients with APOE ε4 status.

Materials And Methods: The relevant English-language articles were identified by searching the Cochrane Library, EMBASE, and PubMed databases.

The role of nanomaterials in revolutionizing ischemic stroke treatment: Current trends and future prospects.

Ischemic stroke has a high disability rate, which leads to irreversible neuronal death. The efficacy of conventional stroke treatments, including thrombolytic and neuroprotective therapies, is constrained by a number of factors, including safety concerns and inefficient drug delivery. The advent of nanomaterials has created new avenues for stroke therapy, facilitating enhanced pharmacokinetic behavior of drugs, effective drug accumulation at the target site, augmented therapeutic efficacy, and concomitant reduction in side effects.

Successfully intravenous thrombolytic therapy in systemic lupus erythematosus-related ischemic stroke: A case report.

Rationale: Stroke is a relatively frequent complication occurring in patients with systemic lupus erythematosus (SLE). The increasing number of patients with Ischemic Stroke secondary to SLE aroused the clinician's concern. SLE thrombosis markers, diagnostic high-resolution magnetic resonance image (HR-MRI), and therapeutic interventions for acute ischemic stroke were recently coming into focus perspectives from the field.

Big data analysis of endovascular treatment for acute ischemic stroke: a study based on bibliometric analysis.

Background:  While bibliometric analyses are prevalent in the medical field, few have focused on ther endovascular treatment for acute ischemic stroke (AIS).

Objective:  To employ big data analysis to examine the research status, trends, and hotspots in endovascular treatment for AIS.

Methods:  We conducted a comprehensive search using the Web of Science (WOS) database to identify relevant articles on the endovascular treatment for AIS from 1980 to the present.

NCAPD3 is a prognostic biomarker and is correlated with immune infiltrates in glioma.

Non-SMC Condensin II Complex Subunit D3 (NCAPD3) has been linked with the genesis and progression of multiple human cancers. Nevertheless, the scientific value and molecular process of NCAPD3 in glioma remain unclear. We explored the level of NCAPD3 expression in pan-cancer by multiple online databases.

Microstructured PVDF Film with Improved Performance as Flexible Infrared Sensor.

Polyvinylidene fluoride (PVDF) is a very promising material for fabricating flexible infrared sensors due to its ferroelectricity as well as excellent flexibility and low fabrication cost. This work focuses on improving PVDF's pyroelectric performance by creating microstructures in the film. Simulation results suggest that the pyroelectric response of PVDF film can be improved if micro groove, square-pit or sinusoidal patterns are created on the film surface, with the grooved film showing the best pyroelectric performance.

Cladding softened fiber for sensitivity enhancement of distributed acoustic sensing.

Fiber-optic distributed acoustic sensing (DAS) technology with high spatial and strain resolutions has been widely used in many practical applications. New methods to enhance the phase sensitivity of sensing fiber are worth exploring to further improve DAS performances, although the standard single-mode fiber (SSMF) has been widely used for DAS technology. In this work, we propose and demonstrate the concept of enhancing the phase sensitivity of DAS by softening the cladding of the sensing fiber, for the first time.

Low-noise high-order Raman fiber laser pumped by random lasing.

Raman fiber lasers (RFLs) have been widely utilized in long-haul optical transmission systems as pump sources for distributed Raman amplification (DRA) to increase transmission distance and capacity. However, RFLs with relatively large temporal intensity fluctuations would deteriorate signal quality due to the transfer of relative intensity noise (RIN). In this Letter, a low-noise high-order RFL common cavity pumped by an ytterbium-doped random fiber laser (YRFL) is proposed and demonstrated for the first time, to the best of our knowledge.

Role of Paip1 on angiogenesis and invasion in pancreatic cancer.

Poly(A)-binding protein-interacting protein 1 (Paip1) was discovered as a modulator of translation initiation as a result of binding to PABP. Increasing evidence suggested that Paip1 has been implicated in several pathogenic roles. However, its clinical significance and underlying molecular mechanisms in Pancreatic cancer (PC) remain uncertain.