Causal association of immune cells and endometriosis: a Mendelian randomization study.

Objective: To investigate the causal effect of immune cells on endometriosis (EMS), we performed a Mendelian randomization analysis.

Methods: Mendelian randomization (MR) uses genetic variants as instrumental variables to investigate the causal effects of exposures on outcomes in observational data. In this study, we conducted a thorough two-sample MR analysis to investigate the causal relationship between 731 immune cells and endometriosis.

Combined contamination of microplastic and antibiotic alters the composition of microbial community and metabolism in wheat and maize rhizosphere soil.

The widespread application of antibiotics and plastic films in agriculture has led to new characteristics of soil pollution. The impacts of combined contamination of microplastics and antibiotics on plant growth and rhizosphere soil bacterial community and metabolisms are still unclear. We conducted a pot experiment to investigate the effects of polyethylene (0.

Venetoclax plus a hypomethylating agent versus cytarabine, aclarubicin, and granulocyte colony-stimulating factor chemotherapy as a first-line therapy for newly diagnosed acute myeloid leukemia: A propensity score-matched analysis.

Background: Both venetoclax plus a hypomethylating agent (VEN/HMA) and cytarabine, aclarubicin, and granulocyte colony-stimulating factor (CAG) are low-intensity regimens for older patients with acute myeloid leukemia (AML) that show good efficacy and safety. It is unknown how VEN/HMA compares with the CAG regimen for the treatment of newly diagnosed AML.

Methods: The outcomes of patients with newly diagnosed AML treated with VEN/HMA were compared with those of patients treated with a CAG-based regimen.

Effects of environmentally relevant concentrations of oxytetracycline and sulfadiazine on the bacterial communities, antibiotic resistance genes, and functional genes are different between maize rhizosphere and bulk soil.

Antibiotic contamination in soil has become a major concern worldwide. At present, it is not clear how two co-existed antibiotics with environmentally relevant concentrations would affect soil bacterial community structure, the abundances of antibiotic resistance genes (ARGs) and functional genes, and whether the effects of antibiotics would differ between rhizosphere and bulk soil. We conducted a greenhouse pot experiment to grow maize in a loess soil treated with oxytetracycline (OTC) or sulfadiazine (SDZ) or both at an environmentally relevant concentration (1 mg kg) to investigate the effects of OTC and SDZ on the rhizosphere and bulk soil bacterial communities, abundances of ARGs and carbon (C)-, nitrogen (N)-, and phosphorus (P)-cycling functional genes, and on plant growth and plant N and P nutrition.

The signature based on seven genomic instability-related genes could predict the prognosis of acute myeloid leukemia patients.

Background: Acute myeloid leukemia (AML) is the most common acute blood malignancy in adults. The complicated and dynamic genomic instability (GI) is the most prominent feature of AML. Our study aimed to explore the prognostic value of GI-related genes in AML patients.

Phosphorus and selenium uptake, root morphology, and carboxylates in the rhizosheath of alfalfa (Medicago sativa) as affected by localised phosphate and selenite supply in a split-root system.

Low availability of phosphorus (P) is a key limiting factor for the growth of many crops. Selenium (Se) is a nutrient for humans that is acquired predominantly from plants. Localised P and Se supply may affect P- and Se-uptake efficiency.

Interactive effects of phosphorus fertilization and salinity on plant growth, phosphorus and sodium status, and tartrate exudation by roots of two alfalfa cultivars.

Background And Aims: Soil phosphorus (P) deficiency and salinity are constraints to crop productivity in arid and semiarid regions. Salinity may weaken the effect of P fertilization on plant growth. We investigated the interactive effects of soil P availability and salinity on plant growth, P nutrition and salt tolerance of two alfalfa (Medicago sativa) cultivars.

The Interaction of Arbuscular Mycorrhizal Fungi and Phosphorus Inputs on Selenium Uptake by Alfalfa ( L.) and Selenium Fraction Transformation in Soil.

Selenium (Se) is a beneficial element to plants and an essential element to humans. Colonization by arbuscular mycorrhizal fungi (AMF) and supply of phosphorus (P) fertilizer may affect the bioavailability of Se in soils and the absorption of Se by plants. To investigate the interaction between AMF and P fertilizer on the transformation of soil Se fractions and the availability of Se in the rhizosphere of alfalfa, we conducted a pot experiment to grow alfalfa in a loessial soil with three P levels (0, 5, and 20 mg kg) and two mycorrhizal inoculation treatments (without mycorrhizal inoculation [-AMF] and with mycorrhizal inoculation [+AMF]), and the interaction between the two factors was estimated with two-way ANOVA.

Phytoextraction of rhenium by lucerne (Medicago sativa) and erect milkvetch (Astragalus adsurgens) from alkaline soils amended with coal fly ash.

Coal fly ash (CFA) is an industrial waste generated in huge amounts worldwide, and the management of CFA has become an environmental concern. Recovery of valuable metals from CFA is one of the beneficial reuse options of CFA. Rhenium (Re) is one of the rarest metals in the Earth's crust and one of the most expensive metals of strategic significance in the world market.

Impacts of coal fly ash on plant growth and accumulation of essential nutrients and trace elements by alfalfa (Medicago sativa) grown in a loessial soil.

Coal fly ash (CFA) is a problematic solid waste all over the world. One distinct beneficial reuse of CFA is its utilization in land application as a soil amendment. A pot experiment was carried out to assess the feasibility of using CFA to improve plant growth and increase the supply of plant-essential elements and selenium (Se) of a loessial soil for agricultural purpose.

Effects of Pisha sandstone content on solute transport in a sandy soil.

In sandy soil, water, nutrients and even pollutants are easily leaching to deeper layers. The objective of this study was to assess the effects of Pisha sandstone on soil solute transport in a sandy soil. The miscible displacement technique was used to obtain breakthrough curves (BTCs) of Br(-) as an inert non-adsorbed tracer and Na(+) as an adsorbed tracer.

Accumulation and precipitation of magnesium, calcium, and sulfur in two Acacia (Leguminosae; Mimosoideae) species grown in different substrates proposed for mine-site rehabilitation.

Premise Of The Study: Few studies have investigated the effects of substrates on the accumulation and precipitation of magnesium, calcium, and sulfur in plants. Acacia stipuligera and A. robeorum growing in their natural habitats with different substrates show different accumulation and precipitation patterns of these elements.

Application of SEM and EDX in studying biomineralization in plant tissues.

This chapter describes protocols using formalin-acetic acid-alcohol (FAA) to fix plant tissues for studying biomineralization by means of scanning electron microscopy (SEM) and qualitative energy-dispersive X-ray microanalysis (EDX). Specimen preparation protocols for SEM and EDX mainly include fixation, dehydration, critical point drying (CPD), mounting, and coating. Gold-coated specimens are used for SEM imaging, while gold- and carbon-coated specimens are prepared for qualitative X-ray microanalyses separately to obtain complementary information on the elemental compositions of biominerals.

Physiological and ecological significance of biomineralization in plants.

Biomineralization is widespread in the plant kingdom. The most common types of biominerals in plants are calcium oxalate crystals, calcium carbonate, and silica. Functions of biominerals may depend on their shape, size, abundance, placement, and chemical composition.

Precipitation of calcium, magnesium, strontium and barium in tissues of four Acacia species (Leguminosae: Mimosoideae).

Precipitation of calcium in plants is common. There are abundant studies on the uptake and content of magnesium, strontium and barium, which have similar chemical properties to calcium, in comparison with those of calcium in plants, but studies on co-precipitation of these elements with calcium in plants are rare. In this study, we compared morphologies, distributional patterns, and elemental compositions of crystals in tissues of four Acacia species grown in the field as well as in the glasshouse.

Morphologies and elemental compositions of calcium crystals in phyllodes and branchlets of Acacia robeorum (Leguminosae: Mimosoideae).

Background And Aims: Formation of calcium oxalate crystals is common in the plant kingdom, but biogenic formation of calcium sulfate crystals in plants is rare. We investigated the morphologies and elemental compositions of crystals found in phyllodes and branchlets of Acacia robeorum, a desert shrub of north-western Australia.

Methods: Morphologies of crystals in phyllodes and branchlets of A.

Dinitrogen-fixing Acacia species from phosphorus-impoverished soils resorb leaf phosphorus efficiently.

Nitrogen (N) and phosphorus (P) resorption from senescing leaves were studied, and the contribution of N and P cycling through litterfall to soil nutrient patchiness was investigated for four Acacia species in the Great Sandy Desert in north-western Australia. N and P concentrations of mature and recently shed leaves were analysed and compared; soils under the canopies of the shrubs and soils in gaps (open areas) between the shrubs were also analysed and compared for N and P concentrations. Mature leaf P concentrations of the plants were considerably lower than the global average values, and N : P ratios of mature leaves were high.