Publications by authors named "Hongguang Sun"

Objective: To understand the dietary patterns of adults and explore their association with iodine nutritional levels and thyroid function in adults.

Design: We randomly collected 5 ml of adult urine samples and measured urinary iodine concentration (UIC) by cerium arsenate-catalysed spectrophotometry. A serum sample of 5 ml was collected for the determination of free triiodothyronine, free thyroxine and thyrotropin, and diet-related information was collected through a FFQ.

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Understanding the transition from meteorological to agricultural drought is crucial for developing effective drought management strategies and early warning systems. This study provides a unique perspective by utilizing hybrid drought indices to explore the temporal and spatial complexities of drought propagation across two large watersheds-California and Mississippi-that feature distinct agro-climatic conditions and irrigation practices. We assess the links between meteorological drought, measured by the Standardized Precipitation Index (SPI), and agricultural drought using three indicators: Vegetation Drought Response Index (VegDRI), GRACE Root Zone Soil Moisture Percentile (SMI), and the Evaporative Demand Drought Index (EDDI).

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  • Cistanche tubulosa, a traditional Chinese herbal medicine, is known for its ability to tonify the kidney and protect the liver, especially in alleviating alcoholic liver disease (ALD) through its phenylethanol glycosides (CPhGs).
  • The study aimed to explore how CPhGs might enhance treatment outcomes for ALD by influencing the gut microbiota and improving the gut-liver axis.
  • Results showed that CPhGs improved ALD symptoms, restored gut barrier function, and corrected gut microbiota imbalances in treated mice, highlighting the importance of gut health in managing liver diseases.
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This study aimed to investigate the effect of phenylethanol glycoside from (CPhGs) on the prevention of bovine serum albumin (BSA)-induced hepatic fibrosis in rats. Investigation of the mechanisms of the anti-hepatic fibrosis effect was focused on CPhGs' influence on the "gut-liver" regulation, including the gut microbiota, intestinal barrier, systemic lipopolysaccharide (LPS) concentration, and LPS-related signaling pathway. The results show that CPhGs restored the diversity of gut microbiota, increased the relative abundance of , and decreased the relative abundance of and in the fibrotic rats.

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Background: Cardiovascular disease (CVD) is a major cause of human mortality and has become the leading cause of death worldwide. Existing studies indicate that structural and functional damage to the main arteries represents a significant risk factor for early vascular lesions and many CVDs.

Aims: This study aimed to explore characteristics of carotid-femoral pulse wave velocity (cfPWV) and its correlation with cardiovascular disease risk factors in healthy individuals.

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This present work consists of investigating the effects of particle size heterogeneity and flow rates on transport-reaction kinetics of CuSO and NaEDTA in porous media, via the combination of a bimolecular reaction experiment and model simulations. In the early stages of transport, a peak is observed in the concentration breakthrough curve of the reactant CuSO, related to the delayed mixing and reaction of the reactants. The numerical results show that an increase in flow rate promotes the mixing processes between the reactants, resulting in a larger peak concentration and a slighter tail of breakthrough curves, while an increase in medium heterogeneity leads to a more significant heavy tail.

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The accumulation of waste plastics has a severe impact on the environment, and therefore, the development of efficient chemical recycling methods has become an extremely important task. In this regard, a new strategy of degradation product-promoted depolymerization process was proposed. Using ,'-dimethyl-ethylenediamine (DMEDA) as a depolymerization reagent, an efficient chemical recycling of poly(bisphenol A carbonate) (BPA-PC or PC) material was achieved under mild conditions.

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Nuclide transport in fractured media involves the advection, dispersion, adsorption, etc. The dispersion and adsorption properties of the rock matrix have spatial variability, which results in an anomalous transport of nuclides. In this study, a time-fractional advection-diffusion equation (t-FADE) model is utilized to capture the sub-diffusion transport behavior with heavy-tail property, including the breakthrough curves (BTCs) of uranium and thorium transport in granite plates.

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There remains a lack of standard models that have all the characteristics of human diseases. Especially in immunological hepatic fibrosis, the bovine serum albumin (BSA)-induced liver fibrosis models have the same developmental mechanisms as human liver fibrosis models, but have received little attention. We standardized a BSA-induced liver fibrosis model in rats and thoroughly assessed its pathological characteristics.

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Understanding high-velocity pollutant transport dependent on the large hydraulic gradient and/or heterogeneity of the aquifer and criteria for the onset of post-Darcy flow have attracted considerable attention in water resources and environmental engineering applications. In this study, a parameterized model is established based on the equivalent hydraulic gradient (EHG) which affected by spatial nonlocality of nonlinear head distribution due to the inhomogeneity at a wide range of scales. Two parameters relevant to the spatially non-local effect were selected to predict the development of post-Darcy flow.

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Contaminants can co-exist and migrate together in the environment, causing complex (and sometimes unexpected) transport dynamics which challenge the efficient remediation of individual contaminants. The co-transport dynamics, however, remained obscure for some contaminants, such as arsenic and micro/nano-plastics (MNPs). To fill this knowledge gap, this study explored the co-transport dynamics of arsenic and MNP particles in saturated soil by combining laboratory experiments and stochastic model analysis.

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Introduction: Participating in multiple competing brand communities simultaneously is common for consumers, which brings challenges for companies to manage brand communities and build strong brand-consumer relationships. Although previous studies have widely examined the drivers and outcomes of consumers' engagement in an individual community, little is known about the multi-competing brand community engagement.

Methods: This paper explores the manifestation, categories, motivational drivers, and consequences of consumers' MBCE through two studies using two different methodologies to fill this gap.

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  • The commercial use of lithium-sulfur batteries (LSBs) has been limited by issues like the "shuttle effect" and low electrical conductivity of lithium polysulfides (LiPSs).
  • Researchers developed a new type of cathode using fig-like hierarchical hollow double-shelled TiN particles which showed significant improvements in sulfur loading and battery capacity (up to 1159 mAh/g).
  • The unique structures of these TiN particles enhanced the surface area for LiPS adsorption and reduced the shuttle effect, resulting in better performance (400 mAh/g at 5C) for lithium-sulfur batteries.
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  • Triple-negative breast cancer (TNBC) is a unique subtype of breast cancer where the role of Transient Receptor Potential (TRP) channel-related genes is not fully understood yet.
  • Researchers used public datasets to identify 19 differentially expressed TRP genes and employed various statistical methods to categorize patients into high-risk and low-risk groups based on gene expression patterns.
  • Their findings revealed that patients in the high-risk group had shorter overall survival, emphasizing the importance of these genes in TNBC prognosis and paving the way for potential targeted therapies.
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Objective: To investigate the value of the noninvasive pressure-strain loop (PSL) technique for assessing left ventricular myocardial work done in patients with essential hypertension.

Methods: Prospectively, 60 patients with hypertension visiting the hospital from August 2020 to July 2021 were collected and divided into the mild hypertension group (SBP 140-159 mmHg, 35 cases) and the moderate-to-severe hypertension group (SBP ≥160 mmHg, 25 cases). Another 40 cases of healthy adults were collected as the control group.

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The present study explores the interaction of water supply and rhizobia inoculation on CO and H O gas exchange characteristics, physiological and biochemical traits in seedlings of Robinia pseudoacacia L. originating from two provenances with contrasting climate and soil backgrounds: the Gansu Province (GS) in northwest China and the Dongbei region (DB) of northeast China. Rhizobia strains were isolated from the 50-years old Robinia forest sites grown in the coastal region of east China.

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Objectives: To explore the value of applying contrast-enhanced ultrasound (CEUS) in adjusting the classification of category 4 nodules in the Chinese-Thyroid Imaging Report and Data System (C-TIRADS).

Methods: The data of preoperative conventional ultrasound and CEUS examinations of 125 C-TIRADS 4 nodules in 109 patients were retrospectively analyzed. We divided the thyroid nodules into two groups based on whether recommend by the guide fine-needle aspiration (FNA).

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Plasma cell mastitis (PCM) and granulomatous mastitis (GM) are the most common inflammatory diseases constituting nonbacterial mastitis (NBM). However, the pathogenesis of NBM remains unclear. In this study, risk factors for NBM were assessed, as well as the pathological features of PCM and GM.

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Objectives: To explore the diagnostic value of contrast-enhanced ultrasound (CEUS) combined with the Chinese Thyroid Imaging Reporting and Data System (C-TIRADS) for differentiation of benign and malignant thyroid nodules.

Methods: A retrospective analysis of the conventional ultrasound and CEUS data of 388 nodules in 355 patients who had undergone thyroid nodule resection was conducted. All nodules had clear pathological results.

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The COVID-19 pandemic has been affecting the United States (U.S.) since the outbreak documented on 2/29/2020, and understanding its dynamics is critical for pandemic mitigation and economic recovery.

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The incidence of papillary thyroid carcinomas (PTCs) has increased rapidly during the past several decades. Until now, the mechanisms underlying the tumorigenesis of PTCs have remained largely unknown. Next-generation-sequencing (NGS) provides new ways to investigate the molecular pathogenesis of PTCs.

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  • Biogenic nano-hydroxyapatite (bio-nHAP) is a promising, eco-friendly material for cleaning heavy metal-contaminated soil, especially lead (Pb(II)), but its transport and reactions in the soil are not fully understood.
  • This study explored how factors like ionic strength, ionic composition, dissolved organic matter, and flow velocity impact the movement and reactions between Pb(II) and bio-nHAP in saturated sand columns.
  • Results indicated that while higher ionic strength and composition increased Pb(II) mobility, they restricted bio-nHAP transport; dissolved organic matter significantly influenced these dynamics, and a new mathematical model was effective in predicting their transport behaviors.
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