Bioinformatics analysis of PANoptosis regulators in the diagnosis and subtyping of steroid-induced osteonecrosis of the femoral head.

In this study, we aimed to investigate the involvement of PANoptosis, a form of regulated cell death, in the development of steroid-induced osteonecrosis of the femoral head (SONFH). The underlying pathogenesis of PANoptosis in SONFH remains unclear. To address this, we employed bioinformatics approaches to analyze the key genes associated with PANoptosis.

Measuring gas discharge in contact electrification.

Contact electrification in a gas medium is usually followed by partial surface charge dissipation caused by dielectric breakdown of the gas triggered during separation of the surfaces. It is widely assumed that such discharge obeys the classical Paschen's law, which describes the general dependence of the breakdown voltage on the product of gas pressure and gap distance. However, quantification of this relationship in contact electrification involving insulators is impeded by challenges in nondestructive in situ measurement of the gap voltage.