Publications by authors named "Hongcheng Guo"

Background: Despite improvement in treatment strategies for atrial fibrillation (AF), a significant proportion of patients still experience recurrence after ablation. This study aims to propose a novel algorithm based on Transformer using surface electrocardiogram (ECG) signals and clinical features can predict AF recurrence.

Methods: Between October 2018 to December 2021, patients who underwent index radiofrequency ablation for AF with at least one standard 10-second surface ECG during sinus rhythm were enrolled.

View Article and Find Full Text PDF

Objective: This study aims to develop an artificial intelligence-based method to screen patients with left ventricular ejection fraction (LVEF) of 50% or lesser using electrocardiogram (ECG) data alone.

Methods: Convolutional neural network (CNN) is a class of deep neural networks, which has been widely used in medical image recognition. We collected standard 12-lead ECG and transthoracic echocardiogram (TTE) data including the LVEF value.

View Article and Find Full Text PDF

Coptis chinensis is a widely used traditional Chinese herbal medicine. In this work, 6 new alkaloids (coptisine A-F, 1-6) and 26 known alkaloids (7-32) were isolated from the chloroform extract of the rhizomes of C. chinensis.

View Article and Find Full Text PDF

Once rice straw has been bioconverted into biofuels, it is difficult to further biodegrade or decompose the saccharification residue (mainly lignin). Taking into account the pyrolysis characteristics of lignin, in this study the saccharification residue was used as a raw material for the preparation of biochar (biochar-SR), a potential soil amendment. Biochar was prepared directly from rice straw (biochar-O) with a yield of 32.

View Article and Find Full Text PDF

Microbial interactions are important for metabolism as they can improve or reduce metabolic efficiency. To improve lignocellulolytic enzyme activity, a series of synergistic microbial consortia of increasing diversity and complexity were devised using fungal strains, including Trichoderma reesei, Penicillium decumbens, Aspergillus tubingensis, and Aspergillus niger. However, when a screened microbial community with cellulolytic capacity was added to the consortia to increase the number of strains, it engendered more microbial interactions with the above strains and universally improved the β-glucosidase activity of the consortia.

View Article and Find Full Text PDF
Article Synopsis
  • Alstonia scholaris, a plant used in Dai ethnic medicine for treating chronic respiratory diseases, contains alkaloids as its primary bioactive components, leading to the development of an investigational drug (AAS) now in phase I/II clinical trials.
  • Researchers employed an ultra-high performance liquid chromatography and mass spectrometry method to identify 35 different alkaloids in AAS, categorized into four types: scholaricine, vallesamine, picrinine, and tubotaiwine.
  • The study also examined how rats metabolize these alkaloids, revealing that scholaricine-type alkaloids enter the bloodstream more easily and identifying 33 compounds in plasma and 40 in urine after administration of the extract.
View Article and Find Full Text PDF

Terahertz (THz) signals measured by means of the spectral-encoding technique with different temporal discrepancies between probe pulses and THz signals are investigated. It is found that imperfect synchronization between the chirped probe and THz pulses induce a distortion and this distortion affects significantly the retrieved THz spectrum if the temporal discrepancy is large. The distortion becomes more prominent if the probe pulse length is less than the optimal chirped probe pulse duration.

View Article and Find Full Text PDF