Publications by authors named "Hongchang Kang"
Macrophages have great plasticity. Typically, there are two of activated macrophages: M1 macrophages and M2 macrophages. Of them, M1 macrophages play a major role in responses that are pro-inflammatory, while M2 macrophages play an important part in responses that are anti-inflammatory.
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- - The study aimed to evaluate the effectiveness of Qingchi San (QCS), a Traditional Chinese Medicine, in treating ulcerative colitis (UC) in mice by targeting specific inflammatory pathways, namely the NF-κB signaling pathway and NLRP3 inflammasome formation.
- - Researchers established a UC model in male mice and measured various health indicators, including body weight, Disease Activity Index (DAI), colon length, and performed histological analysis, as well as testing for several inflammatory markers using different laboratory techniques.
- - Results showed that QCS treatment significantly improved body weight, reduced disease severity (DAI), and enhanced colon health, while also decreasing levels of inflammatory markers and proteins associated with the NF-κB pathway and
Background: Nasopharyngeal carcinoma (NPC) is well-known for its highly metastatic characteristics, but little is known of its molecular mechanisms. New biomarkers that predict clinical outcome, in particular the ability of the primary tumor to develop metastatic tumors are urgently needed. The aim of this study is to investigate the role of FLJ10540 in human NPC development.
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