Publications by authors named "Hongbo Ni"

Article Synopsis
  • Enterocytozoon bieneusi is a common zoonotic pathogen found in both humans and animals, posing significant public health risks, with limited data available on its prevalence in farmed minks and raccoon dogs in China.
  • A study examined 510 animals, revealing an overall E. bieneusi prevalence of 18.6%, with 10.5% in minks and 28.1% in raccoon dogs, and identified ten different genotypes in these species.
  • The detection of several genotypes previously associated with humans in minks and raccoon dogs suggests that these animals could be potential sources of human microsporidiosis, highlighting the need for enhanced monitoring and prevention strategies.
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Blastocystis is a common intestinal protist in humans and animals. Currently, Blastocystis infection in bar-headed geese is unknown. To understand the prevalence and distribution of Blastocystis subtypes in bar-headed geese, fecal samples were collected from 358 bar-headed geese in three regions.

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In recent years, the clinical cases of ENTV-2 infection have increased and become prevalent in several provinces of China. In this study, we reported the occurrence of ENTV-2 in one goat farm in Chongqing, southwest China. The complete genome of an emerged ENTV-2 isolate (designated as CQ2) was sequenced with 7468 bp in length.

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Article Synopsis
  • - The study examines how the parasite Toxoplasma gondii alters host RNA modification profiles to promote its own replication during infection.
  • - Researchers used advanced techniques to analyze RNA modifications in mouse liver, spleen, and serum, finding significant changes, especially in the liver, during acute infection.
  • - The results suggest that these RNA modifications can affect the stability of tRNA and protein translation, enhancing our understanding of host response mechanisms to parasitic infections.
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Cryptosporidium spp. is an important foodborne and waterborne pathogen in humans and animals, causing diarrhoea in humans and respiratory and gastrointestinal diseases in birds. However, reports of Cryptosporidium infection in bar-headed goose are limited.

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Article Synopsis
  • * Phage LHE83 has a contractile tail, a high titer, good tolerance to physical and chemical conditions, and shows a significant growth behavior with a latent period of about 10 minutes and a burst size of 87 pfu/cell.
  • * The study identified OmpA as the receptor for phage LHE83, confirmed through specific assays, and demonstrated a synergistic effect between phage LHE83 and the antibiotic spectinomycin against a drug-resistant E. coli strain, aiding in
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Blastocystis is a protist that is distributed in the gut tract of humans and animals. However, the reports about Blastocystis infection in Tibetan antelope are scarce. We collected 173 Tibetan antelope feces samples from Xinjiang, Qinghai and Xizang, and amplified the SSU rRNA gene of 600 bp region of Blastocystis in our research.

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Avian malaria is a vector-borne parasitic disease caused by Plasmodium infection transmitted to birds by mosquitoes. The aim of this systematic review was to analyze the global prevalence of malaria and risk factors associated with infection in wild birds. A systematic search of the databases CNKI, WanFang, VIP, PubMed, and ScienceDirect was performed from database inception to 24 February 2023.

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Regulatory T cells (Tregs) play a substantial role in inhibiting excessive immune response. A large number of studies have focused on the tissue homeostasis maintenance and remodeling characteristics of Tregs in non-lymphoid tissues, such as the skin, colon, lung, brain, muscle, and adipose tissues. Herein, we overview the kinetics of Treg migration to non-lymphoid tissues and adaptation to the specific tissue microenvironment through the development of tissue-specific chemokine receptors, transcription factors, and phenotypes.

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Background: The gut microbiota plays an essential role in maintaining gut homeostasis and improving performance, with the composition of microbial communities visibly differing across different laying stages in hens and significantly correlating with egg production. To gain further insights into the association between microbial community characteristics and laying periods in Hy-Line variety brown and Isa brown laying hens, we conducted a 16S rRNA amplicon sequencing survey.

Results: Our result revealed the diversity of bacteria in the early laying period was commonly higher than peak, and in Hy-Line variety brown laying hens were generally higher than Isa brown.

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Bovine coronavirus (BCoV) is one of the important pathogens that cause calf diarrhea (CD), winter dysentery (WD), and the bovine respiratory disease complex (BRDC), and spreads worldwide. An infection of BCoV in cattle can lead to death of young animals, stunted growth, reduced milk production, and milk quality, thus bringing serious economic losses to the bovine industry. Therefore, it is necessary to prevent and control the spread of BCoV.

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The fungal community, also known as mycobiota, plays pivotal roles in host nutrition and metabolism and has potential to cause disease. However, knowledge of the gut fungal structure in Caprinae is quite limited. In this study, the composition and diversity of the gut mycobiota of Caprinae animals from different geographical locations (Anhui, Jilin, Guangxi, Shandong, Shanxi, and Tibet) were comprehensively characterized by analyzing the internal transcribed spacer 2 (ITS-2) sequences of the fungal community.

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Deep vein thrombosis is a common clinical peripheral vascular disease that occurs frequently in orthopaedic patients and may lead to pulmonary embolism (PE) if the thrombus is dislodged. pulmonary embolism can be prevented by placing an inferior vena cava filter (IVCF) to intercept the dislodged thrombus. Thus, IVCFs play an important role in orthopaedics.

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  • Most microbiome research has mainly focused on the rumen in ruminants, leaving the gut microbiota less understood; this study investigates the gut microbiota of 30 sheep and goats in China.
  • Using advanced sequencing techniques, the researchers identified 5,046 new microbial genomes, with over half being potentially new species that are not recorded in existing databases.
  • The findings enhance our knowledge of Caprinae gut microbiota diversity and could influence future research on animal health and production.*
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Humans are exposed to infection as pet cats gradually become family members and represent an increasing public health risk worldwide. Toxoplasmosis diagnosis constitutes an important measure for disease prevention and control. In this study, real-time fluorescence quantitative loop-mediated isothermal amplification (qLAMP) and visual LAMP detection technologies were established to conduct tests of based on the membrane DNA extraction method, and the optimal detection mix was determined by adding the protective reagent trehalose and screening the concentrations of Mg and dNTPs.

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Echinococcosis is a foodborne parasitic zoonosis caused by the larvae of . This disease can affect goats and other mammals. In this study, a systematic review and meta-analysis for echinococcosis in global goats were performed based on the following five databases (China National Knowledge Infrastructure [CNKI], VIP Chinese Journal Database, Wanfang Data, PubMed, and ScienceDirect).

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Pullorum disease (PD), caused by the bacterium Salmonella pullorum, severely threatens the health of chickens worldwide, especially in China, and generating concerns for public health safety. Greater awareness of the seroprevalence may facilitate the prevention and control of this disease. We conducted systematic review and meta-analysis on the seroprevalence of PD in chicken flocks across mainland China.

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() infection can cause intestinal inflammation in rodents and significantly alters the structure of gut microbiota. However, the effects of different genotypes on the gut microbiota of rats remain unclear. In this study, acute and chronic infection in Fischer 344 rats was induced artificially by intraperitoneal injection of tachyzoites PYS (Chinese 1 ToxoDB#9) and PRU (Type II).

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The diversity of bacteria and fungi in the gut microbiota of commercial broilers that raised in cages from hatch to the end of the production cycle were examined by an analysis of 3,592 and 3,899 amplicon sequence variants (ASVs), respectively. More than 90% sequences in bacterial communities were related to Firmicutes and Proteobacteria. More than 90% sequences in fungal communities were related to Ascomycota, Basidiomycota, and Glomeromycota.

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Article Synopsis
  • The study investigates the presence of zoonotic enteric pathogens in wild rodents across six provinces in China, specifically focusing on the prevalence of certain bacteria and their potential risk to human health.
  • Out of 536 collected fecal samples, 11.6% tested positive for one pathogen and 3.4% for another, with varying prevalence rates across different regions.
  • This research is significant as it confirms the existence of these pathogens in wild rodents and highlights their potential role as a source of human infection, offering new data on their distribution and genetic diversity.
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Locoregional therapies (LRTs) of hepatocellular carcinoma (HCC) represented by ablation and TACE has become the main means for the clinical treatment of unresectable HCC. Among these, TACE is used throughout the stage Ib to IIIb of HCC treatment. In recent years, immunotherapy led by immune checkpoint inhibitors has become a hot direction in clinical research.

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is a common unicellular protist that lives in the intestines of humans and animals. infection and subtypes in cattle have been reported in several regions. However, the information of infection in cattle in China is still largely scant.

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spp., the causative agent of cryptosporidiosis, can infect a variety of hosts. So far, there has been limited information regarding spp.

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is a protozoan that parasitizes the intestines. A number of hosts of have been found, including human and animals. However, there has been no research on the prevalence of in Tibetan antelope.

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Toxoplasmosis is a zoonotic disease caused by Toxoplasma gondii, which is widespread in warm-blooded animals and humans. Currently, many studies regarding T. gondii infection in sheep have been published worldwide.

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