The kinetic model of cyclohexene-air combustion over a wide temperature range.

Cyclohexene is an important intermediate during the combustion process of hydrocarbon and oxygenated fuels. In view of the lack of study on the combustion of cyclohexene in air, an experimental and modeling study is performed to investigate the chemistry of cyclohexene-air mixtures under a wide temperature range. The shock tube experiments are conducted at pressures of 2 and 10 atm with equivalence ratios of 0.

Diagnostic and prognostic potential of circulating cell-free genomic and mitochondrial DNA fragments in clear cell renal cell carcinoma patients.

Background: There is inconsistent information about the clinical usefulness of circulating cell-free DNA (cfDNA) in plasma from clear cell renal cell cancer (RCC) patients. This is attributed to preanalytical, analytical, and clinical factors that were considered as far as possible in this study.

Methods: cfDNA was extracted from EDTA plasma of healthy people (n=40), non-metastatic (n=145) and metastatic (n=84) RCC patients using the QIAamp Circulating Nucleic Acid Kit.

Risk prediction models for biochemical recurrence after radical prostatectomy using prostate-specific antigen and Gleason score.

Many computer models for predicting the risk of prostate cancer have been developed including for prediction of biochemical recurrence (BCR). However, models for individual BCR free probability at individual time-points after a BCR free period are rare. Follow-up data from 1656 patients who underwent laparoscopic radical prostatectomy (LRP) were used to develop an artificial neural network (ANN) to predict BCR and to compare it with a logistic regression (LR) model using clinical and pathologic parameters, prostate-specific antigen (PSA), margin status (R0/1), pathological stage (pT), and Gleason Score (GS).

Association between IL13 gene polymorphisms and susceptibility to cancer: a meta-analysis.

Background/aims: Interleukin-13 (IL13) is an immunoregulatory cytokine which plays an important role in carcinogenesis through affecting tumor immunosurveillance. Many studies had reported the influence of IL13 rs1800925 and rs20541 polymorphisms on cancer risk, however, with inconclusive results. The aim of the present study was to conduct a meta-analysis to clarify the relationship.

Oxygen free radicals regulate energy metabolism via AMPK pathway following cerebral ischemia.

Objective: One basic consequence of cerebral ischemia is energy depletion, manifested by falling levels of adenosine triphosphate (ATP) and a concomitant rise of adenosine monophosphate (AMP). Energy sensor AMP activated protein kinase (AMPK) can be activated in situations of energy stress to maintain ATP reserves. Here, we investigated the mechanism underlying AMPK pathway following cerebral ischemia in rat hippocampus.