Enhanced electro-catalysis for methanol oxidation reaction performance by edge defects of ordered mesoporous carbon.

Heteroatom-doped carbon materials are widely used to improve the electrocatalytic oxidation of methanol; however, the underlying mechanisms driving this enhancement remain poorly understood. A major challenge lies in developing non-doped carbon supports with tunable intrinsic defect types tailored for metal-based catalysts. In this study, we synthesize a series of ordered mesoporous carbon (OMC) supports with adjustable edge defect densities by varying roasting temperatures and employing a zinc (Zn) evaporation strategy to systematically investigate the impact of edge defects on methanol oxidation reaction (MOR) performance.

Different association of HDLC, apoA-I, and HDL-C/apoA-I with multiple outcomes in HFrEF patients.

Background: High-density lipoprotein-cholesterol (HDLC) has been considered a cardioprotective factor for several decades. However, its association with outcomes in patients with heart failure with reduced ejection fraction (HFrEF) remains controversial. We aimed to investigate the association of HDLC, apolipoprotein A-I (apoA-I), and the HDL-C/apoA-I ratio with multiple outcomes of HFrEF patients and establish prognostic models using machine learning methods.

Do Boys and Girls Display Different Levels of Depression in Response to Mobile Phone Addiction? Examining the Longitudinal Effects of Four Types of Mobile Phone Addiction.

Purpose: Prior research has indicated that mobile phone addiction (MPA) significantly contributes to depression. However, there is a research gap in exploring the distinct impacts of various types of MPA on depression, along with the potential moderating effect of gender. The current study investigated whether the relationship between MPA and depression varies depending on the types of MPA and gender.

Unveiling the Role of β-Glucosidase Genes in 's Secondary Metabolism: A Genome-Wide Analysis.

β-glucosidases (BGLUs) are abundant enzymes in plants that play pivotal roles in cell wall modification, hormone signal transduction, secondary metabolism, defense against herbivores, and volatile compound release. , a perennial herb revered for its therapeutic properties, lacks a comprehensive analysis of its gene family despite the critical role these genes play in plant secondary metabolism. This study aims to perform a genome-wide analysis of the gene family in () to elucidate their functions and regulatory mechanisms in secondary metabolite biosynthesis.

Dynamic B field shimming for improving pseudo-continuous arterial spin labeling at 7 T.

Purpose: B field inhomogeneity within the brain-feeding arteries is a major issue for pseudo-continuous arterial spin labeling (PCASL) at 7 T because it reduces the labeling efficiency and leads to a loss of perfusion signal. This study aimed to develop a vessel-specific dynamic B field shimming method for 7 T PCASL to improve the labeling efficiency by correcting off-resonance within the arteries in the labeling region.

Methods: We implemented a PCASL sequence with dynamic B shimming at 7 T that compensates for B field offsets in the brain-feeding arteries by updating linear shimming terms and adding a phase increment to the PCASL RF pulses.

Lipid-related radiomics of low-echo carotid plaques is associated with diabetic stroke and non-diabetic coronary heart disease.

Carotid plaque radiomics-included models have increased the predictive capacity of cardiovascular risk, but the radiomic features of these models were inconsistent in previous studies. Lipids could be used to select the most important radiomic feature. A retrospective case‒control study was performed in 153 diabetic and 76 non-diabetic patients with carotid plaque detected by ultrasound.

Claustrum volumes are lower in schizophrenia and mediate patients' attentional deficits.

Background: While the last decade of extensive research revealed the prominent role of the claustrum for mammalian forebrain organization, i.e., widely distributed claustral-cortical circuits coordinate basic cognitive functions such as attention, it is poorly understood whether the claustrum is relevant for schizophrenia and related cognitive symptoms.

A Helical Tubular Dyad of [9]Cycloparaphenylene: Synthesis, Chiroptical Properties and Post-Functionalization.

The bottom-up synthesis of discrete tubular molecules that mimic the structural features of carbon nanotubes has been a long-standing pursuit for synthetic chemists. As the shortest segments of armchair-type carbon nanotubes, cycloparaphenylenes are regarded as ideal macrocyclic building blocks for achieving this goal. Here we report the synthesis of a helical tubular molecule featuring three diyne linkers between two site-specifically functionalized [9]cycloparaphenylenes.

Forward design method for the design of panda polarization-maintaining few-mode optical fiber based on artificial neural network.

Panda polarization-maintaining few-mode optical fiber (PPMFMOF) has important research significance in the short distance optical transmission field owing to its advantages of weak nonlinear effects, which is benefit to reduce the use of digital signal processing equipment. Designing a high-performance PPMFMOF quickly and efficiently is expected and yet challenging. In this article, we demonstrated a forward design method for the design of PPMFMOF based on artificial neural network (ANN) to solve the problems of inefficient and time-consuming PPMFMOF design in traditional design method.

Loss tolerance quantum key distribution based on the signal extraction model and advantage distillation technology.

Compared with traditional networks, quantum key distribution (QKD) offers the ultimate resources, allowing two remote users to share secret symmetric keys regardless of the capabilities of eavesdroppers. However, the widespread application of commercial QKD is still challenging due to the low photon detection efficiency and the extremely high transmission loss. Here we demonstrate a fully commercial phase-encoding QKD system using a signal extraction model and advantage distillation technology to suppress detector noise and perform real-time pre-error correction.

Sevoflurane exposure in early life: mitochondrial dysfunction and neurotoxicity in immature rat brains without long-term memory loss.

Neurotoxic effects of general anesthetics, particularly sevoflurane, on pediatric neurodevelopment are a global concern. This study investigated the molecular and metabolic impacts of repeated short exposures to sevoflurane in neonatal rats. Metabolomics analysis revealed significant changes in fatty acid and mitochondrial energy metabolism.

Cold shock proteins CIRBP and RBM3 may indicate hypothermia death: A case report.

Cold-inducible RNA-binding protein (CIRBP) and RNA binding motif protein 3 (RBM3) are both members of the cold shock protein family expressed in response to low-temperature induction. However, their usefulness in the diagnosis of fatal hypothermia in forensic has not been reported. In this study, we report the case of a female who died of fatal hypothermia.

Proteomic alteration in catalpol treatment of Alzheimer's disease by regulating HSPA5/ GPX4.

Alzheimer's disease (AD), a chronic and progressive neurodegenerative disease, is characterized by the deposition of extracellular amyloid plaques and intracellular neurofibrillary tangles. Conventional anti-AD drugs exhibit high toxicity and adversely impact patients' quality of life. Therefore, novel treatments for AD are urgently required.

Congruent Glass Composite Scintillator for Efficient High-Energy Ray Detection.

The scintillator is the most crucial component in the high-energy ray detection system. The available scintillators suffer from the insurmountable drawbacks including poor shaping ability for single crystal and ceramic and low efficiency for glass. Here, a glass composite scintillator is proposed from a congruent crystallization system which possesses both excellent processability and high scintillating yield.

Association between neutrophil-percentage-to-albumin ratio (NPAR) and metabolic syndrome risk: insights from a large US population-based study.

Metabolic syndrome (MetS) is a cluster of conditions that increase the risk of cardiovascular disease and diabetes. This study aimed to investigate the association between Neutrophil-Percentage-to-Albumin Ratio (NPAR) and MetS in a large, nationally representative US population. We analyzed data from 28,178 participants in the National Health and Nutrition Examination Survey (NHANES) 2005-2018.

Machine learning algorithms able to predict the prognosis of gastric cancer patients treated with immune checkpoint inhibitors.

Background: Although immune checkpoint inhibitors (ICIs) have demonstrated significant survival benefits in some patients diagnosed with gastric cancer (GC), existing prognostic markers are not universally applicable to all patients with advanced GC.

Aim: To investigate biomarkers that predict prognosis in GC patients treated with ICIs and develop accurate predictive models.

Methods: Data from 273 patients diagnosed with GC and distant metastasis, who un-derwent ≥ 1 cycle(s) of ICIs therapy were included in this study.

Multi-Center Fetal Brain Tissue Annotation (FeTA) Challenge 2022 Results.

Segmentation is a critical step in analyzing the developing human fetal brain. There have been vast improvements in automatic segmentation methods in the past several years, and the Fetal Brain Tissue Annotation (FeTA) Challenge 2021 helped to establish an excellent standard of fetal brain segmentation. However, FeTA 2021 was a single center study, limiting real-world clinical applicability and acceptance.

Exploring the association between magnesium deficiency and chronic obstructive pulmonary diseases in NHANES 2005-2018.

Chronic Obstructive Pulmonary Disease (COPD) significantly impacts patients' quality of life and burdens healthcare systems. Magnesium is crucial for lung function and reducing respiratory disease risk. This study investigates the association between Magnesium Depletion Score (MDS) and COPD and explores whether inflammatory markers mediate this relationship.

Generation and epitope mapping of novel neutralizing monoclonal antibodies against glycoprotein E2 of CSFV.

Classical swine fever virus (CSFV) is a highly contagious and economically important pathogen threatening pig industry worldwide, the envelope glycoprotein E2 of CSFV is the dominant antigen inducing strong antiviral neutralizing immunity. In this study, 7 monoclonal antibodies (mAbs) with neutralizing potency were generated using E2 protein of CSFV Shimen strain (SM) expressed by eukaryotic cells. Their reactivity with 116 CSFV strains in cell cultures and E2 proteins of 10 subgenotypes in western blots showed different CSFV spectrums they recognized.