Phase regulation of Ni(OH) nanosheets induced by W doping as self-supporting electrodes for boosted water electrolysis.

Developing high-performance and low-cost electrodes for hydrogen and oxygen evolution reactions (HER and OER, respectively) represents a pivotal challenge in the field of water electrolysis. Herein, W doped NiFe LDH nanosheets (NiFe-W/NF) were immobilized on nickel foam (NF) through one-step corrosion engineering, which induced the coexistence of α-Ni(OH) and β-Ni(OH). The doping of large atomic radius W influenced the growth of crystal planes of Ni(OH), promoting the formation of α-Ni(OH), which results in large layer spaces and neatly arranged nanosheets structure.

ANXA1 Enhances the Proangiogenic Potential of Human Dental Pulp Stem Cells.

Dental trauma is highly prevalent in children and adolescents, alongside tooth decay. This condition mainly induces pulp contamination, pulp necrosis, and tooth avulsion in the clinical context. The disturbance to root growth is prone to occur in immature permanent teeth.

Insulin promotes the bone formation capability of human dental pulp stem cells through attenuating the IIS/PI3K/AKT/mTOR pathway axis.

Background: Insulin has been known to regulate bone metabolism, yet its specific molecular mechanisms during the proliferation and osteogenic differentiation of dental pulp stem cells (DPSCs) remain poorly understood. This study aimed to explore the effects of insulin on the bone formation capability of human DPSCs and to elucidate the underlying mechanisms.

Methods: Cell proliferation was assessed using a CCK-8 assay.

Ciwujianoside E inhibits Burkitt lymphoma cell proliferation and invasion by blocking ENO1-plasminogen interaction and TGF-β1 activation.

Burkitt's lymphoma (BL) is a rare and highly aggressive B-cell non-Hodgkin lymphoma. Although the outcomes of patients with BL have greatly improved, options for patients with relapsed and refractory BL are limited. Therefore, there is an urgent need to improve BL therapeutics and to develop novel drugs with reduced toxicity.

Chitosan-taurine nanoparticles cross-linked carboxymethyl chitosan hydrogels facilitate both acute and chronic diabetic wound healing.

Wound dressing diligently facilitate healing by fostering hemostasis, immunoregulation, the angiogenesis, and collagen deposition. Our methodology entails fabricating chitosan-taurine nanoparticles (CS-Tau) through an ionic gelation method. The morphology of CS-Tau was observed utilizing Transmission electron microscopy (TEM), scanning electron microscopy (SEM) and Dynamic Light Scattering (DLS).

Scalable Fabrication of Structurally Stable Polymer Film with Excellent UV-Shielding, Fluorescent, and Antibacterial Capabilities.

This research presents a new approach to facilely fabricating a multifunctional film using polyvinyl alcohol (PVA) as the base material. The film is modified chemically to incorporate various desirable properties such as high transparency, UV-shielding, antibacterial activity, and fluorescence. The fabrication process of this film is straightforward and efficient.

A neutrophil extracellular trap-related risk score predicts prognosis and characterizes the tumor microenvironment in multiple myeloma.

Multiple myeloma (MM) is a distinguished hematologic malignancy, with existing studies elucidating its interaction with neutrophil extracellular traps (NETs), which may potentially facilitate tumor growth. However, systematic investigations into the role of NETs in MM remain limited. Utilizing the single-cell dataset GSE223060, we discerned active NET cell subgroups, namely neutrophils, monocytes, and macrophages.

Boosting oxygen reduction via MnP nanoparticles encapsulated by N, P-doped carbon to Mn single atoms sites for Zn-air batteries.

An electrocatalyst of single-atomic Mn sites with MnP nanoparticles (NPs) on N, P co-doped carbon substrate was constructed to enhance the catalytic activity of oxygen reduction reaction (ORR) through one-pot in situ doping-phosphatization strategy. The optimized MnSA-MnP-980℃ catalyst exhibits an excellent ORR activity in KOH electrolyte with a half-wave potential (E) of 0.88 V (vs.

Facile fabrication of cellulose-based hydrophobic paper via Michael addition reaction.

The inherent highly hydrophilic feature of cellulose-based paper hinders its application in many fields. Herein, a cellulose-based hydrophobic paper was fabricated based on surface chemical modification. Firstly, the hydrophobic acrylate components were bonded to the cellulose acetoacetate (CAA) fibers to obtain CAA graft acrylate (CAA-X) fibers through Michael addition reaction.

Color-Tunable, Excitation-Dependent, and Water Stimulus-Responsive Room-Temperature Phosphorescence Cellulose for Versatile Applications.

Smart-response materials with ultralong room-temperature phosphorescence (RTP) are highly desirable, but they have rarely been described, especially those originating from sustainable polymers. Herein, a variety of cellulose derivatives with 1,4-dihydropyridine (DHP) rings are synthesized through the Hantzsch reaction, giving impressive RTP with a long lifetime of up to 1251 ms. Specifically, the introduction of acetoacetyl groups and DHP rings promotes the spin-orbit coupling and intersystem crossing process; and multiple interactions between cellulose induce clustering and inhibit the nonradiative transitions, boosting long-live RTP.

Effect of Insulin on Bone Formation Ability of Rat Alveolar Bone Marrow Mesenchymal Stem Cells.

The alveolar bone marrow mesenchymal stem cells (ABM-MSCs) play an important role in oral bone healing and regeneration. Insulin is considered to improve impaired oral bones due to local factors, systemic factors and pathological conditions. However, the effect of insulin on bone formation ability of ABM-MSCs still needs to be elucidated.

A binder-free ice template method for vertically aligned 3D boron nitride polymer composites towards thermal management.

Hexagonal boron nitride (BN) is an attractive filler candidate for thermal interface materials, but the thermal conductivity enhancement is limited by the anisotropic thermal conductivity of BN and disordered thermal pathways in the polymer matrix. Herein, a facile and economic ice template method is proposed, wherein BN modified by tannic acid (BN-TA) directly self-assemble to form vertically aligned nacre-mimetic scaffold without additional binders and post-treatment. The effects of the BN slurry concentration and the ratio of BN/TA on three-dimensional (3D) skeleton morphology are fully investigated.

Sprayed Nanovaccine Suppressing Exosomal PD-L1 by Golgi Apparatus Disorganization for Postsurgical Melanoma Immunotherapy.

The anti-PD-L1 immunotherapy has shown promise in treating cancer. However, certain patients with metastatic cancer have low response and high relapse rates. A main reason is systemic immunosuppression caused by exosomal PD-L1, which can circulate in the body and inhibit T cell functions.

Self-supporting electrocatalyst constructed from in-situ transformation of Co(OH) to metal-organic framework to Co/CoP/NC nanosheets for high-current-density water splitting.

Transition metal phosphide (TMP) emerges as a promising electrocatalyst for overall water splitting (OWS). However, conventional TMP materials require exogenous metal ions to participate in coordination reactions, which usually suffer from active site blocking, pronounced intrinsic impedance, and inevitable catalyst shedding at high current density. Herein, a novel in-situ construction strategy has been developed to grow N-doped carbon (NC) enwrapped Co/CoP nanosheets directly onto Co foam (abbreviated as CoF) through a three-step transformation of Co to Co(OH) to Co-Metal-Organic Framework (Co-MOF) to Co/CoP/NC.

Cone-beam computed tomographic characteristics in degenerative temporomandibular joint disease patients with chewing side preference.

Objectives: This study is aimed at assessing the Cone-beam computed tomographic (CBCT) characteristics of temporomandibular joints (TMJ) in degenerative temporomandibular joint disease (DJD) patients with chewing side preference (CSP).

Materials And Methods: CBCT images of 98 patients with DJD (67 with CSP and 31 without CSP) and 22 asymptomatic participants without DJD were measured retrospectively to compare the osteoarthritic changes and the morphology of TMJ. Quantitative analysis of the TMJ radiographic images was performed to present a comparison between the three inter-group groups and between the two sides of the joints.

Interface and electronic structure regulation of Mo-doped NiSe-CoSe heterostructure aerogel for efficient overall water splitting.

Transition metal selenides (TMSes) with cubic pyrite-type crystal structure have been widely explored as electrocatalysts for oxygen evolution reaction (OER), but the insufficient hydrogen evolution reaction (HER) performance hinders the application of overall water splitting. Herein, we designed and prepared a Mo doped NiSe-CoSe heterostructure aerogel as bifunctional electrocatalyst via facile spontaneous gelation and selenium vapor deposition. The active sites on the heterointerface possessed desirable Gibbs free energy of hydrogen adsorption, leading to better HER performance than single NiSe or CoSe.

Multistage interfacial engineering of 3D carbonaceous NiP nanospheres/nanoflowers derived from Ni-BTC metal-organic frameworks for overall water splitting.

The regulation of the multi-dimensional interface plays an important role in optimizing the electron transport and gas mass transfer during catalysis, which is conducive to promoting the electrocatalytic process. Herein, a self-supporting electrode has been developed with the multistage interface within 3D NiP@C nanospheres/nanoflowers arrays derived from metal-organic frameworks (MOFs) as template skeletons and precursors. The constructed nanosphere interface protrudes outward to optimize the contact with the electrolyte while the nanoflower lamellar connection promotes rapid electron transfer and exposes more active sites, and accelerates the gas diffusion with the abundant interspace channels.

Synergistic effect of Fe/CuNC dual single-atom catalyst for CH bond oxidation.

Transition metal-based (Fe, Co, Cu, etc.) single-atom catalysts (SAC) have been widely used in the direct oxidation of ethylbenzene and benzene. However, their catalytic performance is limited by the low metal loading.

Effects of hydrogen rich water and pure water on periodontal inflammatory factor level, oxidative stress level and oral flora: a systematic review and meta-analysis.

Background: Hydrogen rich water (HRW) was used as an auxiliary treatment for periodontitis and peri-implantitis due to its good antioxidant properties. However, the stability of artificially added active hydrogen was far less than that of pure natural active hydrogen, which greatly reduced active hydrogen molecules number in HRW. Meanwhile, the effect of HRW was relatively slow.

C1Q labels a highly aggressive macrophage-like leukemia population indicating extramedullary infiltration and relapse.

Extramedullary infiltration (EMI) is a concomitant manifestation that may indicate poor outcome of acute myeloid leukemia (AML). The underlying mechanism remains poorly understood and therapeutic options are limited. Here, we employed single-cell RNA sequencing on bone marrow (BM) and EMI samples from a patient with AML presenting pervasive leukemia cutis.

Novel multifunctional papers based on chemical modified cellulose fibers derived from waste bagasse.

Most technologies to produce multifunctional paper involved the defect of poor uniformity and stability. Herein, a high stability multi-functional cellulose-based paper was developed via a multiple chemical modification derived from waste bagasse. Firstly, the acetoacetyl groups was anchored on the surface of bagasse cellulose fibers by a heterogeneous transesterification.