Effects of HMGA2 on malignant degree, invasion, metastasis, proliferation and cellular morphology of ovarian cancer cells.

Objective: To analyze effects of high mobility group AT-hook 2 (HMGA2) on malignant degree, invasion, metastasis, proliferation and cellular morphology of ovarian cancer cells.

Methods: Three methods were applied to observe the effect on HMGA2 expression in ovarian cancer cells and ovarian epithelial cells.

Results: After the application of siRNA-HMGA2, number of T29A2-cell clones was decreased, there was significant difference compared with the negative control Block-iT.

[Effect of litchi seed aqueous extracts on learning and memory obstacles induced by D-galactose in mice and its mechanism].

Objective: To investigate the improving effect of Litchi Seed Aqueous Extracts on learning and memory obstacles model and its mechanism.

Methods: The learning and memory obstacles model was incluced by subcutoneous injection of D-galactose (500 mg/kg) for 8 weeks. The model group and treatment groups were given huperzine A (0.

[The prediction value of modified early warning score grade for death of the patients in intensive care unit].

Objective: To study the prediction value and practicality of modified early warning score (MEWS) grade for death of the patients in intensive care unit (ICU).

Methods: According to the predetermined criteria, the clinical data of patients who were admitted to ICU during January 2005 to August 2006(patients with ICU stay exceeding 2 hours were enrolled for study) were collected, and MEWS grade and acute physiology and chronic evaluation II (APACHE II) scores were assessed (90 days as the end point of the observation period). MEWS and APACHE II's receiver operator characteristic (ROC) curve, and their predication index were calculated and compared.