Evaluating Choroidal Vascular Changes in Young Adults With High Myopia Utilizing Swept source optical coherence tomography angiography.

Purpose: Utilizing Swept source optical coherence tomography angiography (SS-OCTA) investigates the changes in the vascular characteristics of the choriocapillaris and larger vascular layers, including Sattler's and Haller's layers, in the macular region of young myopia patients, in order to to Enhance our comprehension of the underlying mechanisms of the pathogenesis of myopia.

Methods: A retrospective analysis was performed on 103 young adults (154 eyes) that underwent SS-OCTA. Axial lengths (AL) were measured, 64 eyes with AL < 26.

Identification and Prediction of Differentially Expressed MicroRNAs Associated with Detoxification Pathways in Larvae of .

poses a severe threat to crops, causing substantial economic losses. The increased use of chemical pesticides has led to resistance in populations. Micro ribonucleic acids (MicroRNAs or miRNAs) are pivotal in insect growth and development.

Chromosome-level genome assembly of the giant ladybug Megalocaria dilatata.

The giant ladybug Megalocaria dilatata (Fabricius) is a potential biocontrol agent and a valuable model for coccinellid genomics and evolutionary biology. However, the lack of a reference genome for M. dilatata has impeded further explorations into its evolution and constrained its use in pest management.

Stable composition of gut microbiome in the Asian ladybeetle Coccinella septempunctata reared on natural and artificial diets.

The Asian ladybeetle, Coccinella septempunctata, is an important insect of predatory natural enemy, which has a strong control effect and application prospects for aphids, whiteflies, mealybugs, and other small-sized pests of agriculture and forestry crops. Gut microbiota composition posed impacts on development of insects. In order to clarify the effect of artificial feed feeding on the intestinal microbial species and structure of C.

Primary Ovarian Small Cell Carcinoma of Pulmonary Type: Analysis of 6 Cases and Review of 31 Cases in the Literatures.

Objective Primary ovarian small cell carcinoma of pulmonary type (SCCOPT) is a rare ovarian tumor with a poor prognosis. The platinum-based chemotherapy is the standard treatment. However, there is little research on the clinical characteristics of SCCOPT and the potential benefits of other treatments due to its low incidence.

Antimicrobial activity, chemical composition and mechanism of action of Chinese chive ( Rottler) extracts.

Chinese chive ( Rottler) is a popular food from species in East and Southeast Asia. Most species possess characteristic aromas and have antimicrobial activity. In this study, the antimicrobial activities of root, leaf, and scape extracts of Chinese chive at different pH levels (3.

Dual Role of Wnt5a in the Progression of Inflammatory Diseases.

Wnt5a is a secreted Wnt ligand that plays a critical role in cellular pathways and inflammatory diseases. The gene encodes two protein isoforms, Wnt5a-long and Wnt5a-short, which differ based on different promoter methylation and have distinct functions. However, the mechanisms of the promoter methylation are unclear.

Complete Mitochondrial Genomes and Phylogenetic Positions of Two Longicorn Beetles, and (Coleoptera: Cerambycidae).

(Motschulsky, 1854) and Gressitt & Rondon, 1970 are two commonly found longicorn beetles from China. However, the lack of sufficient molecular data hinders the understanding of their evolution and phylogenetic relationships with other species of Cerambycidae. This study sequenced and assembled the complete mitochondrial genomes of the two species using the next-generation sequencing method.

Efficacy of keverprazan for duodenal ulcer: A phase II randomized, double-blind, parallel-controlled trial.

Background And Aim: Considering the limitation of varying acid suppression of proton pump inhibitors, this study was aimed to assess the efficacy, safety, and dose-effect relationship of keverprazan, a novel potassium-competitive acid blocker, in the treatment of duodenal ulcer (DU) compared with lansoprazole.

Methods: A randomized, double-blind, double-dummy, multicenter, low-dose, high-dose, and positive-drug parallel-controlled study was conducted to verify the non-inferiority of keverprazan (20 or 30 mg) to lansoprazole of 30 mg once daily for 4 to 6 weeks and dose-effect relationship of keverprazan in the treatment of patients with active DU confirmed by endoscopy.

Results: Of the 180 subjects randomized, including 55 cases in the keverprazan_20 mg group, 61 cases in the keverprazan_30 mg group, and 64 cases in the lansoprazole_30 mg group, 168 subjects (93.

Combined effect of humic acid and vetiver grass on remediation of cadmium-polluted water.

Effective treatment of water pollution is an economic and social requirement globally. Humic acid (HA) is a popular mitigator for such waters. However, the combined effect of HA and restorative plants on cadmium (Cd) remediation is not well understood.

The First Mitochondrial Genomes of the Family Haplodiplatyidae (Insecta: Dermaptera) Reveal Intraspecific Variation and Extensive Gene Rearrangement.

Haplodiplatyidae is a recently established earwig family with over 40 species representing a single genus, Hincks, 1955. The morphology of Haplodiplatyidae has been studied in detail, but its molecular characters remain unclear. In this study, two mitogenomes of Ma & Chen, 1991, were sequenced based on two samples from Fujian and Jiangxi provinces, respectively.

[Neonicotinoid Insecticides Threaten Surface Waters at the National Scale in China].

This study was conducted in response to the current situation in our country in which neonicotinoid pesticides (NNIs) are used in large quantities and their concentration in surface water is gradually increasing. Based on the species sensitivity distribution (SSD), the hazard quotient (HQ) and probabilistic risk assessment (PRA) were used to compare single and mixture risks of NNIs in the surface water in China. The target and recommended values of NNIs in China's surface water quality supervision were also presented.

The management of diabetes mellitus by mangiferin: advances and prospects.

Diabetes mellitus has become one of the most challenging public health problems today. There are still various deficiencies that remain in existing therapeutic drugs. With increasing prevalence and mortality rates, more effective therapeutic agents are required for treatment clinically.

Wnt5a Plays Controversial Roles in Cancer Progression.

Wnt5a is a representative Wnt ligand that regulates multiple cellular functions through the Wnt5a non-classical pathway. Although Wnt5a has been implicated in various pathological conditions, its role in cancer is ambiguous and might involve methyl modifications, distinct mRNA isoforms, as well as different downstream pathways. Therefore, it is an essential factor in cancers' progression (invasion, migration, proliferation, and epithelial-mesenchymal transition), and a potential biomarker for prognosis and treatment.

The highly rearranged mitochondrial genomes of three economically important scale insects and the mitochondrial phylogeny of Coccoidea (Hemiptera: Sternorrhyncha).

The mitochondrial genomes (mitogenomes) of scale insects are less known in comparison to other insects, which hinders the phylogenetic and evolutionary studies of Coccoidea and higher taxa. Herein, the complete mitogenomes of , and were sequenced for Coccoidea. The 15,220-bp long mitogenome of contained the typical set of 37 genes including 13 PCGs, 22 tRNA genes and two rRNA genes; the 15,549-bp long mitogenome of lacked the tRNA gene ; the 15,387-bp long mitogenome of exhibited several shortened PCGs and lacked five tRNA genes.

One-Step Synthesis Heterostructured g-C₃N₄/TiO₂ Composite for Rapid Degradation of Pollutants in Utilizing Visible Light.

To meet the urgent need of society for advanced photocatalytic materials, novel visible light driven heterostructured composite was constructed based on graphitic carbon nitride (g-C₃N₄) and fibrous TiO₂. The g-C₃N₄/TiO₂ (CNT) composite was prepared through electrospinning technology and followed calcination process. The state of the g-C₃N₄ and fibrous TiO₂ was tightly coupled.

A process for production of trehalose by recombinant trehalose synthase and its purification.

The process for production of trehalose using trehalose synthase (TreS) to convert maltose into trehalose in one step is highly desirable in the industry. Nonetheless, the studies on industrial-scale production of trehalose by recombinant TreS in Escherichia coli are still scarce. In this study, a TreS from Pseudomonas putida ATCC47054 was expressed in E.

Bioactivity of CD34+ cells in patients with acute-on-chronic liver failure.

Liver failure is a life-threatened serious disease with many complications and high mortality rate. Stem cells have been applied to replacement therapy, gene therapy and tissue engineering for its capacity of self-renewal and multi-lineage differentiation. To investigate the bioactivity of the peripheral blood hematopoietic stem cells (PBHSC) in patients with acute-on-chronic liver failure, we isolated CD34+ cells from peripheral blood of patients with acute-on-chronic liver failure and healthy controls.

The Catsper channel and its roles in male fertility: a systematic review.

The Catsper channel is a sperm-specific, Ca-permeable, pH-dependent, and low voltage-dependent channel that is essential for the hyperactivity of sperm flagellum, chemotaxis towards the egg, capacitation and acrosome reaction. All of these physiological events require calcium entry into sperm cells. Remarkably, Catsper genes are exclusively expressed in the testis during spermatogenesis, and are sensitive to ion channel-induced pH change, such as NHEs, CaATPase, K channel, Hv1 channel and HCO transporters.