[Expression and Clinical Significance of in Multiple Myeloma].

Objective: To investigate the relative expression level and clinical significance of in serum of patients with multiple myeloma (MM).

Methods: The expression of in serum of 108 MM patients and five MM cell lines including RPMI 8226, NCI-H929, U266, OPM2 and CAG were detected by real-time fluorescence quantitative PCR. The diagnostic value of in MM was evaluated by receiver operating characteristic (ROC) curve analysis.

DBU-Promoted Demethoxylative Thioannulation of Alkynyl Oxime Ethers with Sulfur for the Synthesis of Bisisothiazole-4-yl Disulfides.

An efficient synthesis of bisisothiazole-4-yl disulfides via the demethoxylative thioannulation of alkynyl oxime ethers with odorless elemental sulfur has been first developed. This transformation involves the N-O bond cleavage, the formation of multiple C-S and N-S bonds, providing an efficient way for constructions of both isothiazoles and disulfides. Straightforward elaboration of the products to isothiazole thioethers expands the synthetic utility of this reaction.

Copper-Catalyzed Tandem Sulfuration/Annulation of Propargylamines with Sulfur via C-N Bond Cleavage.

Copper-catalyzed aerobic oxidative sulfuration and annulation of propargylamines with elemental sulfur is described. The tandem reaction involves C-N bond cleavage and the formation of multiple C-S bonds, affording 1,2-dithiole-3-thiones in good to excellent yields with good functional group tolerance.

[Effects of Emission Reductions of Key Sources on the PM Concentrations in the Yangtze River Delta].

The effects of emission reductions of key sources (eight key industries and transportation) on the PM concentrations in the Yangtze River Delta (YRD) were investigated using the weather research forecast-chemistry (WRF-Chem) model in 2013 combined with two normal and enhanced emission reduction scenarios. The SO, NO, PM, and NMVOC emissions in the YRD decrease by 36.3%, 26.

[Characteristics and Source Analysis of Atmospheric Carbonaceous Aerosols in the Cities of Hangzhou and Ningbo].

To investigate the seasonal variations and sources of carbonaceous aerosols in the cities of Hangzhou and Ningbo, field PM sampling was conducted at four representative sites (two urban, one suburban, and one rural) in this region from December 2014 to November 2015. A thermal/optical carbon analyzer was employed to analyze both organic carbon (OC) and elemental carbon (EC) contents in PM by identifying eight different carbon fractions, including OC1, OC2, OC3, OC4+OPC, EC1-OPC, EC2, and EC3. Based on these fractions, OC and EC were defined as OC1+OC2+OC3+OC4+OPC and EC1+EC2+EC3-OPC, respectively; total carbon (TC) was calculated as the sum of OC and EC; and total carbonaceous aerosols (TCAs) were quantified via the sum of organic aerosols (OAs; converted from OC) and EC.

[Exposure Level of Population and Economy in Zhejiang Province Considering the Background of PM in East China].

Using the satellite-derived Fine Particulate Matter (PM) data of global high-precision products during 1998-2012, detailed characteristics of PM distribution over East China and its change are given, and the PM exposure levels for population and economy in Zhejiang is further analyzed in this context. The results show that the overall variability of the regional average value of PM concentration exhibits an increasing trend followed by a decrease during 1998-2012, which is consistent in both the East China and Zhejiang provinces; the turning point occurs around 2007-2009. In the initial years (1998-2000), annual average PM concentrations are below 50 μg·m in the southern part of East China and eastern part of Shandong, while it is 50-75 μg·m in other areas.

[Characteristics of and Factors Affecting Atmospheric CO Concentration in Hangzhou].

In situ measurement of CO concentration(volume fraction) was carried out in both urban and rural areas of Hangzhou from August 2015 to September 2016. The characteristics of CO concentration at the urban site were compared to those at the rural site, and the factors affecting CO concentration in Hangzhou were analyzed via wind direction, weekday-weekend difference in CO concentration, and evolution of CO concentration during the G20 summit. The results revealed that the diurnal variation of CO concentration in both the urban and rural areas presented a single peak curve most of the time, which resulted from the daily evolution of plant photosynthesis/respiration and atmospheric transport conditions.

Temporal and spatial variation in major ion chemistry and source identification of secondary inorganic aerosols in Northern Zhejiang Province, China.

To investigate the seasonal and spatial variations of ion chemistry of fine particles in Northern Zhejiang Province (NZP), China, one year-long field sampling was conducted at four representative sites (two urban, one suburb, and one rural sites) in both cities of Hangzhou and Ningbo from December 2014 to November 2015. Twelve water soluble inorganic ions (WSII) were characterized in this comprehensive study. The annual average of PM concentration in NZP as overall was 66.

[Composition and Regional Characteristics of Atmosphere Aerosol and Its Water Soluble Ions over the Yangtze River Delta Region in a Winter Haze Period].

To investigate the pollution characteristics of water soluble ions in fine atmospheric particles in Yangtze River Delta during the haze period from 18th to 24th Jan 2013, a joint sampling campaign using Andersen sampler was conducted at five cities (including Nanjing, Suzhou, Hangzhou, Lin'an and Ningbo). The analysis of size distribution of these ionic species coupled with the local meteorological conditions may shed some insightful light on the haze formation mechanism in this region. The result has shown: firstly, during the observation period, when Yangtze River Delta located at high pressure or in the front of high pressure, and has a large pressure gradient, the lower atmosphere has a significant airflow divergence in favor of pollutant dispersion; while located in weak low pressure and weak high pressure, the equalizing pressure field is not favorable for pollutant dispersion, especially accompanied with lower atmosphere convergence airflow.

Mucous membrane pemphigoid.

Mucous membrane pemphigoid (MMP) is chronic and frequently associated with exacerbations and remissions of clinical signs and symptoms. Clinicians should use pathologic and immunonologic techniques to help diagnose patients. Multidisciplinary collaboration is often necessary for the diagnosis and proper treatment of MMP.

[Impacts of meteorological factors on atmospheric methane mole fractions in the background area of Yangtze River delta].

Impacts of surface wind direction, surface wind speed, surface air temperature and sunshine hours on the CH4 concentration at Lin'an regional atmospheric background station were studied based on the results from Jan. 2009 to Dec. 2011.

[Characteristics of atmospheric CO2 concentration and variation of carbon source & sink at Lin'an regional background station].

Characteristics of Atmospheric CO2 concentration obtained by Flask measurements were analyzed at Lin'an regional background station from August 2006 to July 2009. According to the simulation results of carbon tracking model, the impact of carbon sources and sinks on CO2 concentration was evaluated in Yangtze River Delta. The results revealed that atmospheric CO2 concentrations at Lin'an regional background station were between 368.

A retrospective study of q-switched alexandrite laser in treating nevus of ota.

Background: The Q-switched alexandrite laser (QSAL) has been clinically proven to be effective in treating nevus of Ota, but a large-scale retrospective study with long-term follow-up has never been performed.

Objective: To evaluate the efficacy of the QSAL in treating nevus of Ota, the laser's long-term side effects, complications associated with the treatments, and the recurrence rate.

Materials And Methods: Eight hundred six patients (651 female, 155 male) with a diagnosis of nevus of Ota who had received a series of QSAL (wavelength 755 nm) treatments were recruited.

A Chinese experience of fractional ultrapulsed CO₂laser for skin rejuvenation.

Background And Objectives: The ablative fractional CO₂ laser has been successfully used in treating photoaged skin in the Caucasian population. However, its application in Asian skin has not been widely reported. The purpose of this study is to observe the efficacy and safety of the protocol 'ActiveFX' for photodamaged facial skin in Chinese patients.

[Comparison analysis of variation characteristics of SO2, NOx, O3 and PM2.5 between rural and urban areas, Beijing].

The concentrations of SO2, NOx, O3 and PM2.5 were observed continuously at Shangdianzi atmospheric background monitoring station and Baolian urban environmental monitoring station from 2006-01-01 to 2006-12-31. The difference of seasonal variation and diurnal variation between rural and urban areas was analyzed.

[Concentrations and size distributions of water soluble ions of atmospheric aerosol at the summit of mount Tai].

In order to research on the air pollutants' long-range transportation in North China, aerosol samples were collected with Andersen cascade sampler at the summit of mount Tai during June 2006, in Shandong Province. The water soluble ionic concentrations were analyzed by IC. It shows that there are three types of size distribution: 1) ions whose mass resided mainly within the accumulation mode with the peak at 0.